铁锰矿物作用下环境中抗生素和抗性基因的降解行为

程鹏飞; 李代微; 颜子竣; 田芹; 戴志聪; 秦好丽; 刘同旭

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中国环境科学 ›› 2025, Vol. 45 ›› Issue (6) : 3359-3369.

农业与农村新污染物

铁锰矿物作用下环境中抗生素和抗性基因的降解行为

程鹏飞^1,3, 李代微², 颜子竣¹, 田芹^2,3, 戴志聪¹, 秦好丽^2,4, 刘同旭³

作者信息 +

The degradation behavior of antibiotics and antibiotic resistance genes in the environment mediated by iron-manganese minerals

CHENG Peng-fei^1,3, LI Dai-wei², YAN Zi-jun¹, TIAN Qin^2,3, DAI Zhi-cong¹, QIN Hao-li^2,4, LIU Tong-xu³

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文章历史 +

摘要

为了阐明铁锰矿物与抗生素和抗性基因间的作用机制,深化对环境中抗生素与抗性基因降解行为的理解,改善抗生素与抗性基因修复技术,本文系统揭示了铁锰矿物对抗生素的多元降解机制:表面Brønsted酸、Lewis酸和羟基位点协同催化抗生素水解;基于半导体特性介导的抗生素光降解;矿物中Fe(III)/Mn(IV)等变价组分直接氧化抗生素或活化过硫酸盐/过氧化氢产生活性自由基实现深度矿化;同时,上述过程产生的自由基也可破坏抗性基因,抑制其迁移转化过程.铁锰矿物已证实可有效去除土壤、水体、污泥及畜禽粪便等环境介质中的抗生素及其抗性基因,其降解行为受环境pH值、有机质含量、共存离子浓度及水分条件等因素动态调控.本文进一步提出未来研究应聚焦于抗生素和抗性基因降解途径和毒性、原位动态表征技术以及铁锰矿物应用工艺等研究方向.

Abstract

To elucidate the interaction mechanisms between iron-manganese minerals and antibiotics/antibiotic resistance genes (ARGs), enhance the understanding of their environmental degradation behaviors, and advance remediation technologies, this study systematically investigates the multifaceted degradation mechanisms of antibiotics by iron-manganese minerals. The mechanisms are explored through the following pathways: synergistic catalysis through surface Brønsted acid sites, Lewis acid sites, and hydroxyl groups promoting antibiotic hydrolysis; semiconductor-mediated photocatalytic degradation via electron-hole pair generation; direct oxidation by redox-active components such as Fe(III)/Mn(IV) coupled with activation of persulfate/hydrogen peroxide to yield reactive species for complete mineralization; concomitant radical-induced damage to ARGs through phosphodiester bond cleavage and base pair destruction, effectively inhibiting their horizontal transfer and evolution. The practical efficacy of iron-manganese minerals has been demonstrated in diverse environmental matrices including soils, aquatic systems, sludge, and livestock manure, with degradation efficiency dynamically regulated by pH, organic matter content, co-existing ions, and moisture conditions. Future research should prioritize establishing integrated databases mapping antibiotic-ARG co-degradation pathways and toxicity profiles, developing in situ dynamic characterization techniques for mineral interface reactions, engineering environment-adaptive mineral- based composite materials.

导出引用

程鹏飞, 李代微, 颜子竣, 田芹, 戴志聪, 秦好丽, 刘同旭. 铁锰矿物作用下环境中抗生素和抗性基因的降解行为[J]. 中国环境科学. 2025, 45(6): 3359-3369

CHENG Peng-fei, LI Dai-wei, YAN Zi-jun, TIAN Qin, DAI Zhi-cong, QIN Hao-li, LIU Tong-xu. The degradation behavior of antibiotics and antibiotic resistance genes in the environment mediated by iron-manganese minerals[J]. China Environmental Science. 2025, 45(6): 3359-3369

中图分类号： X131

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