Study on multimedia environmental fate of typical antibiotics based on level IV fugacity model

WU Ya-lin; XU Jing-xu; LING Wen-cui; SUN Chang-hong; LIU Gui-zhong

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China Environmental Science ›› 2025, Vol. 45 ›› Issue (9) : 5204-5212.

Emerging Contaminants

Study on multimedia environmental fate of typical antibiotics based on level IV fugacity model

WU Ya-lin, XU Jing-xu, LING Wen-cui, SUN Chang-hong, LIU Gui-zhong

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Abstract

The fugacity model is a widely used multimedia environmental fate model for organic pollutants. Multimedia environmental fate of typical antibiotics including ofloxacin and roxithromycin in Liangshui River using reclaimed water was simulated and researched based on level IV fugacity model, and the reliability of model was verified in this study. For another, transfer flux and the main transport process were analysed and identified. Meanwhile, the model key parameters were conducted by sensitivity analysis and uncertainty analysis. The results showed that the simulated concentrations were in good agreement with the measured concentrations, which indicated the simulation effectiveness of the model in the study area. When the environmental system reached equilibrium in the study area, the water advection outflow was identified as the primary export process for target antibiotics in water, while the interfacial exchange process with water phase was the major process for sediment. Sediment was the main reservoir of two antibiotics in the study area because of the mass fraction of ofloxacin and roxithromycin in water and sediment, respectively, were 8.73% and 91.27%, 27.46% and 72.54% at equilibrium. Henry's Law constant (H) significantly influenced the two-phase migration behavior. This study provides theoretical basis and decision-making support for environmental prediction and pollution control of antibiotics in rivers using reclaimed water.

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fugacity model / antibiotics / Liangshui River / multimedia environmental fate

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WU Ya-lin, XU Jing-xu, LING Wen-cui, SUN Chang-hong, LIU Gui-zhong. Study on multimedia environmental fate of typical antibiotics based on level IV fugacity model[J]. China Environmental Science. 2025, 45(9): 5204-5212

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