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Affects of indoor PM10 in Xuanwei on lung cell apoptosis |
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Abstract Indoor PM10 was collected from Hutou village (high incidence area of lung cancer) and Ningjiawan village (low incidence area of lung cancer) respectively in Xuanwei Town; the model of cell apoptosis was set up by exposing the lung epithelial cells A549 to PM10, then detect the cell apoptosis by Annexin-V FITC/PI flow cytometry (FCM). Comparison of the two groups suggested that the total apoptosis rates and the mortality rates of Hutou Group increased significantly. The impact on lung cell apoptosis of indoor PM10 collected form Hutou village was larger than that from Ninjiawang village.
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Received: 13 January 2010
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