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| The contents of five trace elements in Panaxnotoginseng and the associated health risk |
| ZENG Xian-cai1,2, CHAO Si-hong1,2, ZHU Mei-lin1,3, FAN Xiao-ting1,2, JIANG Yan-xue1,2, CAO Hong-bin1,2 |
1. Beijing Key Laboratory of Protection and Application of Chinese Medicinal Resources, Beijing 100875, China;
2. Institute of Resource Ecology and Traditional Chinese Medicine Resources, Beijing Normal University, Beijing 100875, China;
3. Clinical Medicine School of Ningxia Medical University, Yinchuan 750004, China |
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Abstract In order to investigate the contents of Fe、Mn、Al、Zn、Se in Panaxnotoginseng (Sanchi) and evaluate the health risk of these elements for long-term consumers of Sanchi preparations, samples of Sanchi roots were collected in traditional production region and the surrounding areas. The contents of the five trace elements in Sanchi were analyzed by ICP-MSand the non-carcinogenic health risk was evaluated by deterministic estimation and probabilistic estimation. The results show that the average contents of the five trace elements in Sanchiare 1375.84, 108.31, 1213.62, 0.16, 21.99mg/kg, decreased in the order: Al > Fe > Mn > Zn > Se and the order of the hazardous quotient (HQ) values is Fe > Al > Mn > Zn > Se. The HQ valuesare all below 1, implying no non-carcinogenic health riskof individual element for general consumers. However, daily intakes of Fe, Al and Mnare 0.09573, 0.10759, 0.00832mg/(kg·d), which are beyond the corresponding limits for tolerable oral intake from medicinal plants and should be controlled. Probabilistic distribution of hazardous index (HI) values of 5trace elements due to consumption of Sanchi preparation shows that 5.19% of theconsumers havenon-carcinogenic health risk.
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Received: 30 May 2015
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