To investigate the spatiotemporal patterns law of PM_2.5 pollution in China, statistical methods and GIS technology were used to analyze the ground-level PM_2.5 monitoring results in 2014 from 161 cities at or above prefectural level in national air quality monitoring network. The results showed that only 8.1% cities met Grade II standard of ambient air quality standards (GB 3095~2012), and about 26.6% days failed to meet Grade II air quality standards. Diurnal PM_2.5 pollution was least in summer, late spring and early autumn, and was heavy in winter. Daily PM_2.5 concentration followed an indistinctive bimodal curve with minimum value around 16:00 and maximum value around 10:00. The pollution levels were relatively high from midnight to dawn. PM_2.5 pollution was serious in Beijing-Tianjin-Hebei region and its surrounding area, as well as Hubei, Hunan and Anhui. PM_2.5 pollution was least in southeast coast and Yunnan, Tibet. The spatial distribution of PM_2.5 was significantly correlated with spatial distributions of wind speed, relative humidity, and land use. The average ratio of PM_2.5 in PM₁₀ (PM_2.5/PM₁₀ ratio) was 0.591, which has spatial pattern of gradually increasing from northwest to southeast, and was higher in south region than in north region. Monthly average PM_2.5/PM₁₀ ratio was basically stable ranged in 0.55~0.6, excluding higher in January, February, and lower in May. The results could benefit to further understanding on the spatiotemporal patterns of PM_2.5 pollution in China macroscopically, and promote to environmental pollution prevention and control measures accordingly.