The objectives of this paper were: (1) to estimate the biogenic VOC (BVOCs) emissions and its temporal-spatial distributions; and (2) to develop biogenic VOCs emissions inventory of Sichuan based on the remote-sensing data regarding land use and vegetation. In 2012, the total annual biogenic VOCs emissions of Sichuan was estimated to be approximately 1470.82kt, of which isoprene, monoterpenes, and the other VOCs accounted for 429.54kt (29.2%), 445.22kt (30.3%), and 596.06kt (40.5%), respectively. The biogenic VOCs emissions exhibited strong seasonal patterns with emissions in summer being the maximum (accounting for 42.56% of the total) and in winter being the minimum (accounting for 10.43% of the total). The BVOCs emissions were mainly concentrated in the dense woodland areas where the duration of sunlight was relatively long such as Dazhou, Bazhong, Guangyuan, Mianyang , Leshan, Meishan and Panzhihua. The ozone formation potential (OFP) and the secondary organic aerosol formation potentials from the BVOCs were estimated to be 6134kt and 136kt, respectively, implying a significant impact on air quality.