河北潘家口水库氯霉素类抗生素检测及风险评估

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Abstract

Four chloramphenicols, including chloramphenicol, thiamphnicol, florfenicol and florfenicol amine, were investigated in the water from the Panjiakou Reservoir located in Hebei Province, by utilization of solid phase extraction-high performance liquid chromatography-tandem spectrometry (SPE-HPLC-MS/MS). Electrospray ionization and multiple reactions monitoring in positive or negative ionization mode were adopted as the target compounds for qualitative and quantitative analysis. The recoveries of target compounds were all above 90%, with the relative standard deviations (RSDs) ranged between 1.60% and 5.43%. The limits of detection (LODs) and limits of quantification (LOQs) for target compounds were in the range of 0.06~0.29ng/L and 0.18~0.87ng/L, respectively. The detected concentrations of florfenicol in the water samples were in the range of 26.21~233.35ng/L, and detected florfenicol amine were in the range 0.53~8.18ng/L. However, chloramphenicol and thiamphnicol were not detected in the water samples. Additionally, the risk assessments showed that the risk quotient (RQ) for detected antibiotics were below 1, which indicated very low risk to plankton and human health. The RQs of adult and child in wet season were over 100times higher than that in regular level, which might be caused by either the cage culture period or potential impact from water diversion in the reservoir.

Key words： antibiotic metabolite drinking water source risk assessment Panjiakou Reservoir

Received: 30 November 2015

PACS:

X131.2

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	Articles by authors
	LU Cheng
	ZHANG Jun
	WANG Zhao
	CAO Bi-Bo
	XU Ming-Xia
	WANG Yu-Qiu

Cite this article:

LU Cheng,ZHANG Jun,WANG Zhao等. Determination and risk assessment of chloramphenicols in Panjiakou Reservoir, Hebei Province[J]. CHINA ENVIRONMENTAL SCIENCECE, 2016, 36(6): 1843-1849.

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http://manu36.magtech.com.cn/Jweb_zghjkx/EN/ OR http://manu36.magtech.com.cn/Jweb_zghjkx/EN/Y2016/V36/I6/1843

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