人体呼出气中内源性挥发性有机物筛选研究

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Abstract Exhaled breath contains thousands of volatile organic compounds (VOCs), and relevant composition could vary with their health status. A cohort of healthy volunteers (73 students without respiratory disease) was recruited in this work. The breath samples were collected using gas-bag and further analyzed by gas chromatography with mass spectrometric detection and flame ionization detector. Five halides in human exhaled breath were found to have higher concentration levels than those of both indoor and outdoor environments. Among them, 1,1-dichloroethylene concentration in human exhaled breath was detected nearly 20times higher than its indoor air concentration, and about 300 times higher than the outdoor one, which suggests that human breath is an important source of 1,1-dichloroethylene in the environment. By quantitative analysis of exhaled breath of recruited healthy people with parallel comparison with indoor counterparts, eleven endogenous VOCs were detected and can be attributed primarily to humans, including 1,1-Dichloroethene, acetone, 1-hexene, methylcyclohexane, 2-pentanone, trans-2-pentene, 2, 4-dimethylpentane, 3-pentanone, C2Cl4, m-dichlorobenzene and p-dichlorobenzene.

Key words： exhaled breath endogenous endogenous VOCs healthy people GC-FID/MS

Received: 23 February 2016

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	Articles by authors
	LIU Chang
	ZHENG Yun-hao
	LIU Zhao-rong
	YAO Mao-sheng

Cite this article:

LIU Chang,ZHENG Yun-hao,LIU Zhao-rong等. Screening of endogenous volatile organic compounds in human exhaled breath[J]. CHINA ENVIRONMENTAL SCIENCECE, 2016, 36(10): 3112-3117.

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http://www.zghjkx.com.cn/EN/ OR http://www.zghjkx.com.cn/EN/Y2016/V36/I10/3112

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