Thermally activated sulfate was applied to degrade aqueous bisphenol A (BPA) and how some factors affects degradation was investigated, such as substrate concentration, sulfate dosage, applied temperature, initial pH and coexistence of transition metal (Ni₂O₃、Fe⁰、Fe²⁺). Results showed that BPA degradation conformed to pseudo first order reaction kinetics (R²>0.96) and Arrhenius model (R²>0.95) by thermally activated sulfate treatment. Besides, apparent rate constant k_obs was negatively related to initial substrate concentration and in positive correlation with sulfate dosage, applied temperature and initial pH. Also, the reaction activation energy E_a was calculated to be 146.64kJ/mol. Furthermore, adding transition metals exhibited significant enhancement for BPA degradation and optimal ratio was determined as[Fe^x]₀(Fe²⁺, Fe⁰):[PS]₀=1:2.