In order to effectively deal with waste solar panels, Si and PET mixed particles were used as raw materials, separation efficiency of Si and PET mixed particles were studied through orthogonal experiment with different voltage (U), speed (N), electrode spacing (S) and corona electrode angle (θ) conditions, on the basis of the preliminary optimization of single factor test. The results showed that the optimal parameter settings of Si particles in the sorting process were as follows:U=25kV, N=80r/min, S=65mm and θ=50°, and the influencing factors were ordered as followed:S > N > θ > U; the optimal parameter settings of middling in the sorting process were as follows:U=25kV, N=80r/min, S=65mm, and θ=50°, and the influencing factors were ordered as followed:S > N > θ > U; the optimal parameter settings of PET particles in the sorting process were as follows:U=27.5kV, N=80r/min, S=65mm and θ=40°, and the influencing factors were ordered as followed:U > θ > N > S. This study contributes to the efficient recycling of valuable resources from waste solar panels by the electrostatic separation.