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Concentrations distribution and ecological risk assessment of pharmaceuticals and personal care products in Taihu Lake |
LIU Na1, JIN Xiao-wei2, XUE Li-dong2, SHI Jun-zhe3, XU Yan-juan3 |
1. School of Water Resources and Environment, China University of Geosciences(Beijing), Beijing 100083;
2. China National Environmental Monitoring Center, Beijing 100012;
3. Wuxi Environmental Monitoring Center, Wuxi 214023, China |
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Abstract The management of pharmaceuticals and personal care products (PPCPs) in the environment has become a social problem. In present study, concentration of PPCPs was qualitative and quantitative analyzed at 10 sites in Taihu Lake including drinking waters source, estuaries, objective sample sites and control sites according to the request of water-quality target management. In addition, ecotoxicity data of detected PPCPs was collected to conduct ecological risk of PPCPs in Taihu Lake preliminarily. Results showed that 33kinds of PPCPs qualitatively detected in Taihu Lake, and 17 of which were greater than the quantitativedetection limit, with concentrations ranged from 0.03ng/L to 25.77ng/L. Four PPCPs, namely caffeine, sildenafil, ibuprofen and diethyltoluamide were identified as high risk pollutants in Taihu Lake. The two estuaries of Taihu Lake had more compounds detected and posed a greater ecological risk, which should be paid more attention in the future.
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Received: 22 February 2017
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[1] |
Kolpin D W, Furlong E T, Meyer M I, et al. Pharmaceuticals hormones and other organic wastewater contaminants in US streams, 1999-2000:A national reconnaissance[J]. Environ Sa Technol., 2002,36(6):1202-1211.
|
[2] |
OEHHA Proposition 65:a list of chemicals known to the state to cause cancer or reproductive toxicity[EB/OL]. http://oehha.ca.gov/prop65/proposition_65/rop65_list, 2017-07-07.
|
[3] |
王丹,隋倩,吕树光,等.黄浦江流域典型药物和个人护理品的含量及分布特征[J]. 中国环境科学, 2014,34(7):1897-1904.
|
[4] |
欧丹云,陈彬,陈灿祥,等.九龙江下游河口水域抗生素及抗性细菌的分布[J]. 中国环境科学, 2013,33(12):2243-2250.
|
[5] |
薛保铭,杨惟薇,王英辉,等.钦州湾水体中磺胺类抗生素污染特征与生态风险[J]. 中国环境科学, 2013,33(9):1664-1669.
|
[6] |
王丹,隋倩,赵文涛,等.中国地表水环境中药物和个人护理品的研究进展[J]. 科学通报, 2014,59(9):743-751.
|
[7] |
Zhang Q Q, Ying G G, Pan C G, et al. Comprehensive evaluation of antibiotics emission and fate in the river basins of China:source analysis, multimedia modeling, and linkage to bacterial resistance[J]. Environmental Science & Technology, 2015,49(11):6772-82.
|
[8] |
秦伯强,胡维平,陈伟民.太湖水环境演化过程与机理[M]. 北京:科学出版社, 2004:19-28.
|
[9] |
刘丹,刘济宁,吴晟旻,等.太湖水体中对硝基苯酚的分布特征及风险评价[J]. 中国环境科学, 2017,37(2):761-767.
|
[10] |
王志强,张依章,张远,等.太湖流域宜溧河酚类内分泌干扰物的空间分布及风险评价[J]. 环境科学研究, 2012,(12):1351-1358.
|
[11] |
张盼伟,周怀东,赵高峰,等.太湖表层沉积物中PPCPs的时空分布特征及潜在风险[J]. 环境科学, 2016,37(9):3348-3355.
|
[12] |
Zuo Q, Lu C A, Zhang W L. Preliminary study of phosphorus runoff and drainage from a paddy field in the Taihu Basin[J]. Chemosphere, 2003,50(6):689-694.
|
[13] |
Zhou L J, Wu Q L, Zhang B B, et al. Occurrence, spatiotemporal distribution, mass balance and ecological risks of antibiotics in subtropical shallow Lake Taihu, China[J]. Environmental Science Processes & Impacts, 2016,18(4):500-513.
|
[14] |
Chen J Q, Guo R X. Access the toxic effect of the antibiotic cefradine and its UV light degradation products ontwo freshwater algae[J]. Journal of Hazardous Materials, 2012,209-210:520-523.
|
[15] |
Robinson A A, Belden J B, Lydy M J. Toxicity of fluoroquinolone antibiotics to aquatic organisms[J]. Environ-mental Toxicology and Chemistry, 2005,24(2):423-430.
|
[16] |
De Liguoro M, Fioretto B, Poltroneri C, et al. The toxicity of sulfamethazine to Daphnia magna and its additivity to other veterinary sulfonamides and trimethoprim[J]. Chemosphere, 2009,75(11):1519-1524.
|
[17] |
厉文辉.抗生素分析方法及其典型区域污染特征研究[D]. 北京:中国科学院生态环境研究中心, 2013.
|
[18] |
Suter G W. Applicability of indicator monitoring to ecological risk assessment[J]. Ecological Indicators, 2001,1:101-12.
|
[19] |
Moermond C T, Kase R, Korkaric M, et al. CRED:Criteria for reporting and evaluating ecotoxicity data[J]. Environmental Toxicology and Chemistry, 2015,35(5):1297-1309.
|
[20] |
刘娜,金小伟,王业耀,等.生态毒理数据筛查与评价准则研究[J]. 生态毒理学报, 2016,11(3):1-10.
|
[21] |
EMEA. Committee for Medicinal Products for Veterinary Use (CVMP):Guideline on Environmental Impact Assessment for Veterinary Medicinal Products Phase Ⅱ[M]. European Medicines Agency Veterinary Medicines and Inspections, London, UK. 2004a.
|
[22] |
EMEA. Committee for Medicinal Products for Human Use (CHMP):Guideline on the environmental risk assessment of medicinal products for human use[M]. European Medicines Agency Pre-Authorization Evaluation of Medicines for Human Use, London, UK. 2004b.
|
[23] |
Chapman P M, Fairbrother A, Brown D. A critical evaluation of safety (uncertainty) factors for ecological risk assessment[J]. Environ Toxicol Chem, 1998,17:99-108.
|
[24] |
Wood R J, Mitrovic S M, Kefford B J. Determining the relative sensitivity of benthic diatoms to atrazine using rapid toxicity testing:a novel method[J]. Science of the Total Environment, 2014,485:421-427.
|
[25] |
Gaudet-Hull A M, Rayburn J R, Bantle J A, et al. FETAX interlaboratory validation study:Phase Ⅱ testing[J]. Environ-mental Toxicology and Chemistry, 1994,13(10):1629-1637.
|
[26] |
Dietrich S, Ploessl F, Bracher F, et al. Single and combined toxicity of pharmaceuticals at environmentally relevant concen-trations in Daphnia magna-A multigenerational study[J]. Chemosphere, 2010,79(1):60-66.
|
[27] |
Li M H. Acute toxicity of 30pharmaceutically active compounds to freshwater planarians, Dugesia japonica[J]. Toxicological & Environmental Chemistry, 2013,95(7):1157-1170.
|
[28] |
Brain R A, Johnson D J, Richards S M, et al. Effects of 25pharmaceutical compounds to Lemnagibba using a seven-day static-renewal test[J]. Environmental toxicology and chemistry, 2004,23(2):371-382.
|
[29] |
Zenobio J E, Sanchez B C, Archuleta L C, et al. Effects of triclocarban, N, N-diethyl-meta-toluamide, and a mixture of pharmaceuticals and personal care products on fathead minnows (Pimephalespromelas)[J]. Environmental toxicology and chemistry, 2014,33(4):910-919.
|
[30] |
Kim J W, Ishibashi H, Yamauchi R, et al. Acute toxicity of pharmaceutical and personal care products on freshwater crustacean (Thamnocephalusplatyurus) and fish (Oryzias latipes)[J]. The Journal of toxicological sciences, 2009,34(2):227-232.
|
[31] |
Roderer G. Inhibition of cytokinesis and formation of giant cells in Posterioochromonasmalhamensis by organic lead compounds and other agents (author's transl)[J]. Protoplasma, 1979,99(1/2):39-51.
|
[32] |
Zuccarelli M D, Ingermann R L. Calcium-induced quiescence of sperm motility in the bluegill (Lepomismacrochirus)[J]. Journal of Experimental Zoology Part A:Ecological Genetics and Physiology, 2007,307(10):590-599.
|
[33] |
Rocco L, Frenzilli G, Zito G, et al. Genotoxic effects in fish induced by pharmacological agents present in the sewage of some Italian water-treatment plants[J]. Environmental toxicology, 2012,27(1):18-25.
|
[34] |
US EPA.Pesticide Ecotoxicity Database (Formerly:Environmental Effects Database (EEDB))[EB/OL]. Environ-mental Fate and Effects Division, USEPA, Washington, DC, 1992.
|
[35] |
Parolini M, Pedriali A, Binelli A. Application of a biomarker response index for ranking the toxicity of five pharmaceutical and personal care products (PPCPs) to the bivalve Dreissenapolymorpha[J]. Archives of environmental contamination and toxicology, 2013,64(3):439-447.
|
[36] |
刘娜,金小伟,王业耀,等.三唑酮对青鳉鱼和大型溞不同测试终点的毒性效应评价[J]. 中国环境科学, 2016,36(7):2205-2211.
|
[37] |
Han S, Choi K, Kim J, et al. Endocrine disruption and consequences of chronic exposure to ibuprofen in Japanese medaka (Oryzias latipes) and freshwater cladocerans Daphnia magna and Moinamacrocopa[J]. Aquatic Toxicology, 2010,98(3):256-264.
|
[38] |
Bjerregaard P, Hansen P R, Larsen K J, et al. Vitellogenin as a biomarker for estrogenic effects in brown trout, Salmotrutta:laboratory and field investigations[J]. Environmental Toxicology and Chemistry, 2008,27(11):2387-2396.
|
[39] |
刘娜,金小伟,王业耀,等.我国地表水中药物与个人护理品污染现状及其繁殖毒性筛查[J]. 生态毒理学报, 2015,10(6):1-12.
|
[40] |
乔敏,王春霞,黄圣彪,等.太湖梅梁湾水体和沉积物中有机污染物的遗传毒性[J]. 中国环境科学, 2006,26(2):224-227.
|
[41] |
郭广慧,吴丰昌,何宏平,等.太湖水体多环芳烃生态风险的空间分布[J]. 中国环境科学, 2012,32(6):1032-1039.
|
|
|
|