大通湖表层水体中抗生素赋存特征与风险

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Abstract The concentrations of 12 antibiotics.classified into sulfanilamides (SAs), trimethoprim (TMP), quinolones (QNs) and tetracyclines (TCs) in surface water of the Datong Lake, were detected by UPLC-MS/MS in order to assess the occurrence and risk level of typical antibiotics. 11 antibiotics were detected expect for ofloxacin, and the total concentrations of antibiotics ranged from 0.19ng/L to 261.89ng/L in surface water. The highest average concentration was sulfadiazine (37.41ng/L), followed by sulfamethoxazole (12.34ng/L) > sarafloxacin (8.55ng/L) > enrofloxacin (8.04ng/L) > trimethoprim (7.56ng/L) > chlortetracycline (3.92ng/L). The detection frequencies of sulfa-diazine, tetracycline, chlortetracycline, sarafloxacin, trimethoprim and sulfamethoxazole, were over 50%, could be higher than 50%. The pollution level was similar to those of other rivers and lakes in China expect for sulfadiazine and enrofloxacin. Spatially, the pollution level of antibiotics in Datong Lake showed distinct differences. The results of environmental risk assessment indicated that sulfamethoxazole, ciprofloxacin and sarafloxacin, RQ>1, might pose a significant risk to aquatic organisms of the Datong Lake. The cumulative risk of S2, S3 and S6 were higher, and the main factors were enrofloxacin and sarafloxacin, sulfamethoxazole and ciprofloxacin, ciprofloxacin and sarafloxacin, respectively. The health risk indexes for adults and children, calculated for 11 antibiotics based on the acceptable daily intake through drinking water, ranged from 8.74×10^-8 to 9.17×10^-3, with children having a higher index than adults.

Key words： Datong Lake surface water antibiotic occurrence ecological risk

Received: 08 June 2017

PACS:	X52
	X171

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	LIU Xiao-hui
	LU Shao-yong

Cite this article:

LIU Xiao-hui,LU Shao-yong. Occurrence and ecological risk of typical antibiotics in surface water of the Datong Lake, China[J]. CHINA ENVIRONMENTAL SCIENCECE, 2018, 38(1): 320-329.

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http://manu36.magtech.com.cn/Jweb_zghjkx/EN/ OR http://manu36.magtech.com.cn/Jweb_zghjkx/EN/Y2018/V38/I1/320

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