We analyzed the spatial distribution and variation trend of PBL SO₂ over China using the satellite retrieved data from the ozone monitoring instrument (OMI) sensor. In the long term scale, the SO₂ presented an obvious decline trend. The regional mean value has reduced 0.041DU (about 13.2%) from 2005 to 2016. The SO₂ showed an obvious periodic variation, the value was higher in winter and lower in summer. The smallest and largest value appeared in July and December with 0.246 and 0.404DU respectively. The wavelet analysis finding showed that the variation of SO₂ have primary period in 10months scale. In the spatial scale, there were 4 higher value regions over Circum-Bohai-Sea region, Sichuan Basin, Yangtze River Delta, and Pearl River Delta. The Largest value was up to 1.1DU over Bohai Rim Economic Zone. The higher value areas of the Circum-Bohai-Sea region in North China has been extended to the Yangtze River Delta region, with the southward extension to the Pearl River Delta. The SO₂ in the Sichuan Basin have higher values due to the influence of topography and weather characteristics. In the Tibetan Plateau and Northwest China, the SO₂ concentration was low, indicated the background value characteristics, the multi-yearly average SO₂ was about 0.05DU. There were obvious differences in the spatial distribution of variation trends of SO₂ over China. The range of variation was between -0.70 and 0.15DU. The gradual decreasing region of SO₂ appeared in high-value areas, such as Circum-Bohai-Sea region, Sichuan Basin, the Yangtze River and the Pearl River Delta. The largest reduction was about 61%, which reduced by about 0.55 and 0.45DU over Sichuan Basin and the Pearl River Delta from 2005 to 2016, respectively. The gradually increasing regions were mainly in the western and northern region, and the southeast coast excluding the Pearl River Delta. The maximum growth was about 0.15DU.