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| Study on arsenic bioaccessibility in soil based on Chinese gastrointestinal digestion characteristics |
| ZHENG Rui1,2, PENG Chao2, ZHONG Mao-sheng2,3, JIANG Lin2, HAN Dan2, ZHANG Dan2 |
1. School of Environment and Tourism of Capital Normal University, Beijing 100048, China;
2. Beijing Municipal Research Institute of Environmental Protection, National Engineering Research Centre of Urban Environmental Pollution Control, Beijing Key Laboratory for Risk Modeling and Remediation of Contaminated Sites, Beijing 100037, China;
3. School of Environment of Beijing Normal University, Beijing 100875, China |
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Abstract In order to considering the digestive characteristics of Chinese people, gastric and intestinal juice formulated in the Chinese Pharmacopoeia were used as digestive solutions in measuring as bioaccessibility of 13 soil samples collected from Dalian, Hunan and Guangxi in this study. The correlation between soil physicochemical parameters and As bioaccessibility was investigated, and the effects of enzymes and the pH of gastrointestinal fluid as well as the digestive duration on As bioaccessibility were explored. The results showed that the bioaccessibility of As in stomach and intestine were 5.03%~44.54% and 10.77%~51.46% respectively, with the arithmetic means at 18.08% and 29.32%. Two most significant factors influencing the As bioaccessibility in stomach were w(TAs) and w(TP), followed by w(TAl), pH of soil samples and w(TOM). The most significant factors in intestine were w(TAs), bioaccessible As in stomach and w(TP), followed by pH of soil samples, w(TAl) and w(TOM). The bioaccessible As in stomach was decreased due to the addition of pepsin while no significant change was observed by adding typsin to the digestive solution in intestine. The bioaccessibility of As reached the peaks at the pH 0.9 and 5.0 in stomach and intestine respectively and approach the maximum levels relatively stable by about 1.0h and 4.0h of extraction in stomach and intestine respectively. Therefore, digestion simulations for 1.0h in stomach fluid at pH 0.9 and for 4.0h in intestine fluid at pH 5.0 were recommended for As bioaccessibility measurement. The study also indicates that it is of great significance to further developing the bioaccessibility method based on the characteristics of Chinese gastrointestinal digestion.
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Received: 30 May 2018
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