A grid-stirring turbulence generation device was applied with the grid rotation frequency of 0, 500, 1000and 1500Hz, corresponding to the turbulent energy dissipation rate ranged in 0~8.93×10^-3m²/s³, to investigate the effect of flow turbulence on the growth of Microcystis aeruginosa under high light intensity and phosphorus deficiency conditions. Under high light intensity (8000lx), the growth of Microcystis was significantly inhibited, and the algal concentration under the static condition was only 47.7% of that under normal light intensity. However, turbulence could alleviate the effect of high light environment to a certain extent. Among them, the algae concentration in the 1000Hz group was the highest, which was 1.8times higher compared to the static group. The Chl-a content in the high light intensity group was 1.52 to 1.78 times that of normal light conditions, which indicated that high light intensity might not promote the growth and division of algal cells, and the accumulation of Chl-a might be the defense response of Microcystis aeruginosa to the adverse conditions of high light intensity. In the absence of phosphorus, the algal biomass was only 1/6~1/4 of that in normal nutritional conditions. However, with the increase of turbulence intensity, the algae biomass increased slightly and the Chl-a concentration increased significantly from the initial concentration. Among them, the 1000Hz group was found to be with the best growth. Flow turbulence can alleviate the harsh environments such as high light intensity and phosphorus deficiency for algae growth and accumulation of Chl-a might be the defense response of algal cells to the adverse environment.