Tröger's base (TB) and sulfonated polysulfone (SPSF) with sulfonation degree of 20% as blending materialswere used to prepare a novelSPSF/TB blending ultrafiltration membranes by non-solvent induced phase separation process (NIPS), N-methyl-2-pyrrolidone (NMP), ethylene glycol monomethyl ether (EGM) and deionized water were worked as solvent, pore-forming agent and coagulation bath, respectively. The effects of blending ratio on membrane structure, water contact angle, porosity, pure water flux, BSA rejection rate and antifouling property were investigated. The results showed that the surface contact angle of blending membrane was reduced, the hydrophilicity was enhanced, the pure water flux was increased, and the hydrophilicity and the antifouling ability of the blending membranes were significantly improved with the increase of SPSF mass ratiosince the original neutral amines and sulphonic acid has been changed into corresponding ammonium salts and sulphonates after blending. It was further revealed that the morphology and structure of SPSF/TB blending membrane were completely changed into a gradient sponge pore structurewith the increase of SPSF mass ratio. Especially, the polymer crosslinkedshowed a unique network structuredue to the formation of organic polymer salts at a larger blending ratio. The pure water flux (JWC) and the pure flux recovery rate (FRR) of SPSF/TB^3-15reached 274.92~343.21L/(m²·h) (operating pressure of 0.1MPa) and 61.11%~67.45%, respectively, increased by 42.88%~78.37% and 67.4%~84.8% compared with pure TB membrane. The oil-bearing wastewaterrejection of SPSF/TB⁵ reached more than 98.52%, the water flux and the FRR reached 199.1L/(m²·h), and 61.6% after 3 cycles, respectively under the optimum conditions.