8:2氟调聚羧酸在虾夷扇贝体内的蓄积、分布与转化

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Abstract The uptake, tissue distribution and biotransformation of 8:2fluorotelomer carboxylic acid (8:2FTCA) in liver, gills, sexual gland, mantle and adductor muscle tissues of the scallop Patinopecten yessoensis were investigated. The highest concentration of 8:2 FTCA was detected in the liver, and the maximum uptake rate of 8:2 FTCA in the gills. Five metabolic products, including 8:2 fluorotelomer unsaturated carboxylic acid (8:2 FTUCA), 7:3 fluorotelomer carboxylic acid (7:3 FTCA), perfluorooctanoic acid (PFOA), perfluorononanoic acid (PFNA) and perfluoroheptanoic acid (PFHpA) were identified in scallops. 7:3 FTCA and PFOA were major metabolites, which tended to accumulate in gills and liver. The biotransformation of parent compound 8:2 FTCA was dominantly occurred in gills, where the metabolites were present at the highest concentrations. The biotransformation pathway of 8:2 FTCA in P. yessoensis was proposed for the first time. Compared with the biotransformation behavior of 8:2 FTCA in rainbow trout, the distinct species differences were observed in the yield and half-life of metabolites in P. yessoensis. These results indicated that 8:2 FTCA can be easily transformed in P. yessoensis, and the detection of PFOA, PFNA and PFHpA indicates that exposure to 8:2 FTCA may be an indirect route of exposure to PFCAs in scallops.

Key words： fluorotelomer carboxylic acid perfluocarboxylic acids tissue distribution biotransformation Patinopecten yessoensis

Received: 03 March 2020

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X174

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	Articles by authors
	GUO Meng-meng
	GUO Jiao
	LI Feng-ling
	WANG Zhi
	LIU Xiao-yu
	ZHAI Yu-xiu
	TAN Zhi-jun

Cite this article:

GUO Meng-meng,GUO Jiao,LI Feng-ling等. Uptake, distribution and biotransformation of 8:2 fluorotelomer carboxylic acid (8: 2FTCA) in scallops (Patinopecten yessoensis)[J]. CHINA ENVIRONMENTAL SCIENCECE, 2020, 40(10): 4607-4616.

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http://www.zghjkx.com.cn/EN/ OR http://www.zghjkx.com.cn/EN/Y2020/V40/I10/4607

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