双酚A类似物的雄性生殖毒性研究进展

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Abstract This paper examined studies on bisphenol analogues and male reproductive toxicity with the focus on analyzing the data involving toxic effects of bisphenol analogues on the testis and organization structure, weight and histological structure of epididymis, hormone levels and sperm parameters in mammals, and investigating several essays about fish and amphibian animal research. All BPA analogues had reproductive hazards in these animals regardless of dose, mode of exposure, or species of animals, which suggested that these BPA analogues had more significant male reproductive toxicity than that of BPA on which researches were still debating. However, the majority of data points on the male reproductive toxicity of BPA analogues was limited from a few laboratories and quality control was also hard to discern. Therefore, to obtain more reliable and repeatable results, the findings on male reproductive toxicity of BPA analogues need to be verified by more laboratories, and the quality of animal experiments should be strictly controlled.

Key words： bisphenol A analogues male reproductive toxicity quality control

Received: 09 October 2020

PACS:	X171.5
	R114

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	LI Hong-mei
	XIONG Yi-ming
	XU Hai-ming
	LI Yuan-yuan
	LI Jin-bo
	QIN Zhan-fen

Cite this article:

LI Hong-mei,XIONG Yi-ming,XU Hai-ming等. Research progress in male reproductive toxicity of bisphenol A analogues[J]. CHINA ENVIRONMENTAL SCIENCECE, 2021, 41(6): 2939-2945.

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http://www.zghjkx.com.cn/EN/ OR http://www.zghjkx.com.cn/EN/Y2021/V41/I6/2939

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