环渤海区域典型河流下游水体中抗生素赋存状况及风险评估

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Abstract This study was conducted to characterize the occurrences and accumulation of antibiotics in surface water of each river's downstream in Bohai Rim Basin and to evaluate their ecological risk and human health risk. The results indicate that 50 antibiotics falling into 6 categories were detected in the lower reaches of four major rivers (Xiaoling, Luanhe, Yellow River and Daliao) in Bohai Rim Basin. Off all kinds of antibiotics, β-Ls, MLs and QNs were dominant in those waterbodies of the basin, of which the concentration of Penicillin G was the highest, up to 353.13ng/L. Compared with other rivers in China, The concentration of antibiotics ranged from 124.50ng/L to 489.16ng/L whose average concentration over the study area was rated at a moderate pollution level, but higher than that in other rivers of China. The accumulation level of different rivers was rated in the order as: Xiaoling River>Daliao River>Luanhe River>Yellow River. In addition, amoxicillin, anhydroerythromycin and erythromycin presented higher ecological risk to sensitive aquatic species than did tetracycline, oxytetracycline, enrofloxacin, ofloxacin and cinoxacin which were evaluated at a moderate ecological risk. According to the threshold of the human health risk value of target antibiotics (2.53×10^-7~6.79×10^-3), the pollution level of the antibiotics in the Bohai Rim Basin did not become a health threat to people yet.

Key words： the Bohai Rim Basin water antibiotics risk assessment

Received: 08 June 2021

PACS:	X522
	X826

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	Articles by authors
	ZHAO Fu-qiang
	GAO Hui
	LI Rui-jing
	JIN Shuai-chen
	ZHANG Hai-bo
	LI Shi-sheng
	ZHANG Ke-yu
	SHU Qin
	NA Guang-shui

Cite this article:

ZHAO Fu-qiang,GAO Hui,LI Rui-jing等. Occurrences and risk assessment of antibiotics in water bodies of major rivers in Bohai Rim Basin[J]. CHINA ENVIRONMENTAL SCIENCECE, 2022, 42(1): 109-118.

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http://www.zghjkx.com.cn/EN/ OR http://www.zghjkx.com.cn/EN/Y2022/V42/I1/109

[1]	Jiang X, Liu L, Chen J, et al. Antibiotic resistance genes and mobile genetic elements in a rural river in Southeast China: Occurrence, seasonal variation and association with the antibiotics [J]. Science of the Total Environment, 2021, 778: 146131.
[2]	Zhang G, Liu X, Lu S, et al. Occurrence of typical antibiotics in Nansi Lake's inflowing rivers and antibiotic source contribution to Nansi Lake based on principal component analysis-multiple linear regression model [J]. Chemosphere, 2020, 242: 125269.
[3]	Aydin S, Aydin M E, Ulvi A, et al. Antibiotics in hospital effluents: occurrence, contribution to urban wastewater, removal in a wastewater treatment plant, and environmental risk assessment [J]. Environmental Science and Pollution Research, 2019, 26(1): 544-558.
[4]	Zainab S M, Junaid M, Xu N, et al. Antibiotics and antibiotic resistant genes (ARGs) in groundwater: A global review on dissemination, sources, interactions, environmental and human health risks [J]. Water Research, 2020, 187: 116455.
[5]	Wang Z, Du Y, Yang C, et al. Occurrence and ecological hazard assessment of selected antibiotics in the surface waters in and around Lake Honghu, China [J]. Science of the Total Environment, 2017, 609: 1423-1432.
[6]	Kairigo P, Ngumba E, Sundberg L R, et al. Occurrence of antibiotics and risk of antibiotic resistance evolution in selected Kenyan wastewaters, surface waters and sediments [J]. Science of the Total Environment, 2020, 720: 137580.
[7]	Pan M, Chu L M. Occurrence of antibiotics and antibiotic resistance genes in soils from wastewater irrigation areas in the Pearl River Delta region, southern China [J]. Science of the Total Environment, 2018, 624: 145-152.
[8]	Xie H, Hao H, Xu N, et al. Pharmaceuticals and personal care products in water, sediments, aquatic organisms, and fish feeds in the Pearl River Delta: Occurrence, distribution, potential sources, and health risk assessment [J]. Science of the Total Environment, 2019, 659: 230-239.
[9]	Pan M, Chu L M. Phytotoxicity of veterinary antibiotics to seed germination and root elongation of crops [J]. Ecotoxicology and Environmental Safety, 2016, 126: 228-237.
[10]	Chen H, Liu S, Xu X R, et al. Tissue distribution, bioaccumulation characteristics and health risk of antibiotics in cultured fish from a typical aquaculture area [J]. Journal of Hazardous Materials, 2018, 343: 140-148.
[11]	Luo Y, Mao D, Rysz M, et al. Trends in antibiotic resistance genes occurrence in the Haihe River, China [J]. Environmental Science & Technology, 2010, 44(19): 7220-7225.
[12]	Wang G, Zhou S, Han X, et al. Occurrence, distribution, and source track of antibiotics and antibiotic resistance genes in the main rivers of Chongqing city, Southwest China [J]. Journal of Hazardous Materials, 2020, 389: 122110.
[13]	Zhang Q Q, Ying G G, Pan C G, et al. A comprehensive evaluation of antibiotics emission and fate in the river basins of China: Source analysis, multimedia modelling, and linkage to bacterial resistance [J]. Environmental Science & Technology, 2015, 49(11): 6772-6782.
[14]	Lyu J, Yang L, Zhang L, et al. Antibiotics in soil and water in China-a systematic review and source analysis [J]. Environmental Pollution, 2020, 266: 115147.
[15]	Qiao M, Ying G G, Singer A C, et al. Review of antibiotic resistance in China and its environment [J]. Environment International, 2018, 110: 160-172.
[16]	Li S, Shi W, Li H, et al. Antibiotics in water and sediments of rivers and coastal area of Zhuhai City, Pearl River estuary, south China [J]. Science of the Total Environment, 2018, 636: 1009-1019.
[17]	Yan C, Yang Y, Zhou J, et al. Antibiotics in the surface water of the Yangtze Estuary: occurrence, distribution and risk assessment [J]. Environmental Pollution, 2013, 175: 22-29.
[18]	Hu Y, Yan X, Shen Y, et al. Antibiotics in surface water and sediments from Hanjiang River, Central China: Occurrence, behavior and risk assessment [J]. Ecotoxicology and Environmental Safety, 2018, 157: 150-158.
[19]	Xu W, Zhang G, Zou S, et al. A preliminary investigation on the occurrence and distribution of antibiotics in the Yellow River and its tributaries, China [J]. Water Environment Research, 2009, 81(3): 248-254.
[20]	Lei K, Zhu Y, Chen W, et al. Spatial and seasonal variations of antibiotics in river waters in the Haihe River Catchment in China and ecotoxicological risk assessment [J]. Environment International, 2019, 130: 104919.
[21]	张晓娇, 柏杨巍, 张远, 等. 辽河流域地表水中典型抗生素污染特征及生态风险评估[J]. 环境科学, 2017, 38(11): 4553-4561. Zhang X J, Bai Y W, Zhang Y, et al. Occurrence, distribution, and ecological risk of antibiotics in surface water in the Liaohe River Basin, China [J]. Environmental Sciences, 2017, 38(11): 4553-4561.
[22]	曲衍波, 王霞, 王世磊, 等. 环渤海地区城市规模扩张与质量增长的时空演变及耦合特征[J]. 地理研究, 2021, 40(3): 762-778. Qu Y B, Wang X, Wang S L, et al. Spatio-temporal evolution and coupling characteristics of urban scale expansion and quality growth in Bohai Rim [J]. Geographical Reseach, 2021, 40(3): 762-778.
[23]	徐成龙, 庄贵阳. 基于环境规制的环渤海地区工业集聚对生态效率的时空影响[J]. 经济经纬, 2020, 37(3): 11-19. Xu C L, Zhuang G Y. Spatial and temporal impact of industrial agglomeration on ecological efficiency in Bohai Economic Rim [J]. Economic Survey, 2020, 37(3): 11-19.
[24]	Zou S, Xu W, Zhang R, et al. Occurrence and distribution of antibiotics in coastal water of the Bohai Bay, China: impacts of river discharge and aquaculture activities [J]. Environmental Pollution, 2011, 159(10): 2913-2920.
[25]	Hernando M D, Mezcua M, Fernandez-Alba A R, et al. Environmental risk assessment of pharmaceutical residues in wastewater effluents, surface waters and sediments [J]. Talanta, 2006, 69(2): 334-342.
[26]	封梦娟, 张芹, 宋宁慧, 等. 长江南京段水源水中抗生素的赋存特征与风险评估[J]. 环境科学, 2019, 40(12): 5286-5293. Feng M J, Zhang Q, Song N H, et al. Occurrence characteristics and risk assessment of antibiotics in source water of the Nanjing Reach of the Yangtze River [J]. Environmental Sciences, 2019, 40(12): 5286-5293.
[27]	U.S. EPA. Guidance on selecting age groups for monitoring and assessing childhood exposures to environmental contaminants [EB/ OL]. https://www.epa.gov/risk/guidance-selecting-age-groups-monitoringand-assessing-childhood-exposures-environmental.
[28]	Carvalho I T, Santos L. Antibiotics in the aquatic environments: A review of the European scenario [J]. Environment International, 2016, 94: 736-757.
[29]	Binh V N, Dang N, Anh N T K, et al. Antibiotics in the aquatic environment of Vietnam: Sources, concentrations, risk and control strategy [J]. Chemosphere, 2018, 197: 438-450.
[30]	Kümmerer K. Antibiotics in the aquatic environment – A review – Part Ⅰ [J]. Chemosphere, 2009, 75(4): 417-434.
[31]	张慧, 郭文建, 朱晨, 等. 山东省主要河流中抗生素污染组成及空间分布特征[J]. 中国环境监测, 2019, 35(1): 89-94. Zhang H, Guo W J, Zhu C, et al. Composition and spatial distribution characteristics of antibiotics in main rivers of Shandong Province[J]. Environmental Monitoring in China, 2019, 35(1): 89-94.
[32]	Li L, Liu D, Zhang Q, et al. Occurrence and ecological risk assessment of selected antibiotics in the freshwater lakes along the middle and lower reaches of Yangtze River Basin [J]. Journal of Environmental Management, 2019, 249: 109396.
[33]	Murata A, Takada H, Mutoh K, et al. Nationwide monitoring of selected antibiotics: Distribution and sources of sulfonamides, trimethoprim, and macrolides in Japanese rivers [J]. Science of the Total Environment, 2011, 409(24): 5305-5312.
[34]	Hossain A, Nakamichi S, Habibullah-Al-Mamun M, et al. Occurrence and ecological risk of pharmaceuticals in river surface water of Bangladesh [J]. Environmental Research, 2018, 165: 258-266.
[35]	Ergie A A, Leng Y, Wang J. Antibiotics and resistance genes in Awash River Basin, Ethiopia [J]. Ecohealth, 2019, 16(3): 441-453.
[36]	Arikan O A, Rice C, Codling E. Occurrence of antibiotics and hormones in a major agricultural watershed [J]. Desalination, 2008, 226(1-3): 121-133.
[37]	Da Silva B F, Jelic A, Lopez-Serna R, et al. Occurrence and distribution of pharmaceuticals in surface water, suspended solids and sediments of the Ebro river basin, Spain [J]. Chemosphere, 2011, 85(8): 1331-1339.
[38]	丁剑楠, 刘舒娇, 邹杰明, 等. 太湖表层水体典型抗生素时空分布和生态风险评价[J]. 环境科学, 2021, 42(4): 1811-1819. Ding J N, Liu S J, Zou J M, et al. Spatiotemporal distributions and ecological risk assessments of typical antibiotics in surface water of Taihu Lake [J]. Environmental Sciences, 2021, 42(4): 1811-1819.
[39]	Feng L, Cheng Y, Zhang Y, et al. Distribution and human health risk assessment of antibiotic residues in large-scale drinking water sources in Chongqing area of the Yangtze River [J]. Environmental Research, 2020, 185: 109386.
[40]	杨宇轩. 骆马湖表层水典型抗生素赋存特征及沉积物吸附行为研究[D]. 徐州: 中国矿业大学, 2020. Yang Y X. Occurrence characteristics of typical antibiotics in surface water of luoma lake and adsorption behavior on sediments [D]. Xu Zhou: China University of Mining and Technology, 2020.
[41]	巫明毫, 沙菁洲, 侯永斌, 等. 四川典型水域表层水体抗生素残留特征与风险评估[J]. 中国测试, 2020, 46(10): 78-85. Wu M H, Sha J Z, Hou Y B, et al. Characteristics and risk assessment of antibiotic residues in surface water of typical waters in Sichuan [J]. China Measurement & Test, 2020, 46(10): 78-85.
[42]	张微, 潘灿平. 一些农药和兽药的ADI值[J]. 中国兽药杂志, 2005, 39(3): 39-45. Zhang W, Pan C P. Acceptable daily in takes for agricultural and veterinary chemicals [J]. Chinese Journal of Veterinary Drug, 2005, 39(3): 39-45.
[43]	张慧, 郭文建, 刘绍丽, 等. 南四湖和东平湖表层水体中抗生素污染特征和风险评价[J]. 环境化学, 2020, 39(12): 3279-3287. Zhang H, Guo W J, Liu S L, et al. Contamination characteristics and risk assessment of antibiotics in surface water of Nansi Lake and Dongping Lake [J]. Environmental Chemistry, 2020, 39(12): 3279-3287.
[44]	刘瀚阳. 典型抗生素在淮河流域(安徽段)水生生态系统中的分布特征、沉降趋势及其风险评估[D]. 芜湖: 安徽师范大学, 2020. Liu H Y. Occurrence, deposition trend and risk assessment of typical antibiotics in the aquatic environment of the Anhui section of Huaihe River Basin [D]. WuHu: Anhui Normal University, 2020.
[45]	谢全模, 陈云, 万金泉, 等. 东莞市饮用水源地中抗生素分布特征及风险评价[J]. 环境科学学报, 2020, 40(1): 166-178. Xie Q M, Chen Y, Wan J Q, et al. 2020. Occurrence, distribution and risk assessment of antibiotics in drinking water source in Dongguan [J]. Acta Scientiae Circumstantiae, 2020, 40(1): 166-178.
[46]	张国芳. 不同水处理工艺对典型喹诺酮类抗生素的去除规律及潜在风险评估[J]. 净水技术, 2020, 39(6): 106-111, 124. Zhang G F. Removal rules and potential risk assessment of typical quinolone antibiotics by different water treatment processes [J]. Water Purification technology, 2020, 39(6): 106-111, 124.