纳米颗粒物对肺表面活性物质界面性质的影响

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Abstract Nano-particles (NPs) such as nano-silica, nano-carbon powder, nano-zinc oxide, nano-cerium oxide, nano-silicon carbide and nano-iron tetroxide were used as representatives to study their effects on the interface properties of pulmonary surfactant (PS). The results shown that NPs had adsorption effects on both phospholipid and protein components in PS, and nano-silica and nano-ferric tetroxide had the strongest adsorption capacity for phospholipid and protein components, respectively, with adsorption rates of 89.3% and 82.5%. The existence of NPs would lead to the increase of the surface tension of PS solution, among which the effect of nano-silica was the most significant. Particles such as nano-silicon carbide and nano-silicon dioxide can cause the inward shrinkage/outward expansion of the π-A isotherm of the PS film, and the higher the particle concentration, the more obvious the surface pressure change. In addition, PS also had an effect on the hydration kinetic diameter and Zeta potential of NPs, resulting in the change of its dispersion state. It can be seen that NPs can change the composition and interface of PS by changing the composition and interface of PS.

Key words： nanoparticles pulmonary surfactant interfacial chemical properties adsorption lung health

Received: 25 October 2021

PACS:

X503.1

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	Articles by authors
	LIU Dan
	LI Jie
	CAO Yan
	GENG Ying-xue
	CHAI Xiao-long
	JIANG Fan-shu
	SHI Wei-meng
	ZHAO Qun
	TIAN Sen-lin

Cite this article:

LIU Dan,LI Jie,CAO Yan等. Effect of nano-particles on interfacial chemical properties of pulmonary surfactant[J]. CHINA ENVIRONMENTAL SCIENCECE, 2022, 42(5): 2379-2386.

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http://www.zghjkx.com.cn/EN/ OR http://www.zghjkx.com.cn/EN/Y2022/V42/I5/2379

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