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| Testing techniques and assessment systems for endocrine disrupting chemicals |
| SONG Shi-lin1,2, LI Yuan-yuan1,2, XIONG Yi-ming1,2, LI Jin-bo1,2, QIN Zhan-fen1,2 |
1. State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China;
2. University of Chinese Academy of Sciences, Beijing 100049, China |
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Abstract Endocrine disrupting chemicals (EDCs) are a major kind of pollutants that have been highly concerned by the academia and the international community in recent years because of their known and potential hazards to ecological safety and human health. This paper introduces the currently widely recognized methods for testing EDCs, mainly involving the disrupting activities of estrogen, androgen and thyroid pathways. The characteristics and limitations of different levels of methods show that the detection of endocrine disrupting activity and the evaluation of adverse effects cannot be well correlated, which is the technical bottleneck in identifying EDCs. We further review the strategies for testing and assessing EDCs in developed countries such as the European Union and the United States and compare their characteristics and commonalities, from which we discussed the current situation and problems of EDCs research in China and provide some advices on the construction of testing and assessing system of EDCs in China.
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Received: 20 October 2022
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