全氟烷基酸在大型溞体内的竞争富集作用及机制

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Abstract Perfluoroalkyl acids (PFAAs) are a class of ubiquitous organic pollutants in aquatic environment. The PFAAs can be accumulated in various organisms, and thus induce diverse toxic effects. By studying the bioconcentration of short-chain PFAAs in Daphnia magna under exposure conditions with and without long-chain PFAAs, we herein analyzed the uptake rate constant (k_u), elimination rate constant (k_e), and bioconcentration factors at steady state (BCF_ss) of PFAAs in Daphnia magna, and subsequently attempted to uncover mechanisms underpinning the influence of long-chain PFAAs on shorter chain PFAA bioaccumulation. It revealed positive linear associations between k_u or BCF_ss and the numbers of perfluorinated carbon, membrane-water distribution coefficients, protein-water distribution coefficients, and PFAA-protein association constants. Moreover, longer chain PFAAs inhibited the bioconcentration of shorter chain PFAAs, reducing the BCF_ss to 56%~80%. Such a reduction would be caused by competitive binding to proteins between longer and shorter chain PFAAs.

Key words： PFAS bioaccumulation competitive effect Daphnia magna fatty acid-binding protein emerging pollutants

Received: 21 June 2023

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X131

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	Articles by authors
	XIAO Lu
	ZHANG Shang-wei
	CHENG Hao
	YU Dan-feng
	JIANG Xiao-man
	HU Die-xuan
	WEN Wu
	XIA Xing-hui

Cite this article:

XIAO Lu,ZHANG Shang-wei,CHENG Hao等. Competitive effect and mechanisms for bioconcentration of perfluoroalkyl acids in Daphnia magna[J]. CHINA ENVIRONMENTAL SCIENCECE, 2024, 44(1): 489-498.

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http://www.zghjkx.com.cn/EN/ OR http://www.zghjkx.com.cn/EN/Y2024/V44/I1/489

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