基于氟吡菌酰胺残留量概率分布评估膳食风险

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Abstract The exposure risk of fluopyram in cucumber was comprehensively evaluated for different dietary consumption groups in China based on its residual characteristics. A rapid and sensitive ultra performance liquid chromatography-tandem mass spectrometry method was developed for the determination of fluopicolide in cucumber, with limit of quantitation (LOQ) of 0.001mg/kg and retention time of 2.6 min. The half-lives of fluopyram in cucumber was 2.6~6.7d, indicated it was an easily digestible pesticide. The final levels of fluopyram was < LOQ~0.130mg/kg, which were lower than the maximum residue limit standard of China and the world. Probabilistic and deterministic models showed that fluopyram did not pose an unacceptable short-term dietary risk to Chinese dietary consumers (%ARfD, 0.081%~2.527%), whereas there was an unacceptable long-term dietary risk (%ADI, 105.740%~ 528.147%), of which cucumber accounted for 0.325%~1.107%. In addition, the long-term dietary risks of children aged 2~6 years (367.156%~528.147%) were significantly higher than that of other age groups (334.940%~105.740%) (p＜0.05). In summary, we should further focus on the negative effects of fluopyram exposure under multiple exposure pathways and joint risk amplification in the follow-up study, especially for vulnerable children.

Key words： fluopyram residual characteristics concentration difference probabilistic model risk assessment

Received: 07 October 2023

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X56

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	HAN Wen-hao
	ZHANG Ming-hao
	LIU Feng-jiao
	CHEN Yi-fu
	CHENG You-pu
	WU Yan-bing
	CHEN Zeng-long

Cite this article:

HAN Wen-hao,ZHANG Ming-hao,LIU Feng-jiao等. Dietary risk assessment based on the probability distribution of fluopyram residues[J]. CHINA ENVIRONMENTAL SCIENCECE, 2024, 44(5): 2714-2723.

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http://www.zghjkx.com.cn/EN/ OR http://www.zghjkx.com.cn/EN/Y2024/V44/I5/2714

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