基于皮肤擦拭采样的石化从业人群OCPs皮肤暴露评估

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Abstract This study assessed the dermal exposure to organochlorine pesticides (OCPs) in 30 petrochemical workers from Maoming, a prototypical petrochemical and agricultural city in South China, with an equal gender distribution. Swipe samples from exposed skin areas, such as foreheads and palms, and cloth-covered regions, including forearms and calves, were analyzed using gas chromatography-mass spectrometry (GC-MS). The investigation detected 10 OCPs with frequencies ranging from 1.7% to 57%, with Hexachlorocyclohexane (HCH) occurring more frequently (35%) than dichlorodiphenyltrichloroethane (DDT) (5.3%). OCPs concentrations varied significantly (P<0.0001), with levels ranging to 3050ng/m², in descending order from forehead, to palms, forearms, and finally calves. Dermal absorption doses (DAD_derm) and hand-to-mouth exposure doses (DAD_oral) were predominantly attributable to HCH, which contributed more than 60% of the exposure, and ranged up to 13ng/(kg·d) and 0.24ng/(kg·d), respectively. The head and neck areas were the most substantial contributors to DAD_derm (87%). Despite slightly higher exposure levels in females, the differences were not statistically significant (P>0.05). Health risk assessments indicated that cancer risks from exposure were within safe limits (<10^-4), although females exhibited a marginally higher risk.

Key words： petrochemical workers organochlorine pesticides dermal exposure health risk

Received: 02 February 2024

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X503.1

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	GUO Jian
	LUO Xiao-jun
	ZENG Yan-hong
	MAI Bi-xian

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GUO Jian,LUO Xiao-jun,ZENG Yan-hong等. Evaluating dermal exposure to organochlorine pesticides among petrochemical workers based on skin wipe sampling[J]. CHINA ENVIRONMENTAL SCIENCECE, 2024, 44(9): 5286-5292.

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http://www.zghjkx.com.cn/EN/ OR http://www.zghjkx.com.cn/EN/Y2024/V44/I9/5286

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