Abstract：A study was carried out on the acute toxicity effects of Trimethyltin chloride (TMT) on Chlorela pyrenoidosa,Daphnia magna and Danio rerio. The results suggested that the growth of Chlorela pyrenoidosa was inhibited in the TMT of experimental content, the inhibiting effect increased significantly with the concentration increasing. The part of Chlorela pyrenoidosa cells even would be lethal in the higher concentration group(5.31,20mg/L). The toxic effects of TMT had the highest toxicity to Chlorela pyrenoidosa and Daphnia magna, and the 96h-EC50 and 48h-LC50 was 0.46mg/L and 0.087mg/L, respectively. while was high-toxic to Danio rerio, the 96h-LC50 concentration was 2.45mg/L. EC50/LC50 changed regularly with the test time. The two main reasons leading to the potential threat to the aquatic organisms could be the neurotoxicity and lipophilic property of TMT.
