Abstract:The polluting flow containing soil-water interfaces from urban areas was simulated under laboratory conditions in order to better evaluate the toxicity of contaminants in natural water. Single and joint toxicity of galaxolide and cadmium were evaluated to Daphnia magna in waters containing suspended solids and suspended solids-free water. EC50 of Daphnia magna in waters containing suspended solids exposed to galaxolide at 24h and 48h was 2.455 and 1.187 mg/L, and that exposed to Cd was 0.384 and 0.304 mg/L, respectively. In suspended solids -free water EC50 of Daphnia magna exposed to galaxolide at 24h and 48h was 0.533 and 0.189mg/L, and that exposed to Cd was 0.359 and 0.244 mg/L, respectively. Using the 1:1 toxicity method, while the exposure time was 24h and 48h, the joint toxicity of galaxolide and Cd was antagonistic in waters containing suspended solids, respectively. However, in suspended solids-free water it was synergistic, respectively.