Abstract：To explore the acute effect of air pollution and hospital admissions for cardiovascular and cerebrovascular diseases in Lanzhou, unidirectional retrospective case-crossover design was used to analyze the relation of daily average concentration of air pollutants (PM10、SO2 and NO2) in short-time increased with the cardiovascular and cerebrovascular diseases hospitalizations from 2001 to 2005. The results showed that the unidirectional case-crossover design with 1:2 matched pairs had the highest odds ratios between air pollutants and hospital admissions. After being adjusted for meteorological factors, an increase of 10μg/m3 in PM10 was significantly associated with 1.002(95%CI: 1.001~1.003) and 1.002(95%CI: 1.001~1.003) at 3 days lag increase respectively for total circulatory diseases (ICD10:I00~I99) and cardiovascular disease (ICD10:I00~I52); an increase of 10μg/m3 in SO2 was associated with 1.005(95%CI:1.000~1.009) for total circulatory diseases hospitalizations; a 10μg/m3 increment in NO2 was significantly associated with hospital admissions on value of ORs 1.022(95%CI:1.014~1.030) for the total circulatory diseases at 1day lag, 1.021(95%CI: 1.011~1.030) for cardiovascular disease at 2 days lag, 1.019(95%CI:1.005~1.033) for cerebrovascular diseases (ICD10: I60~I69) at 2 days lag respectively. In the multiple air pollutant models, an increase of 10μg/m3 in PM10 was also associated with cardiovascular and cerebrovascular diseases hospitalizations, the OR values of NO2 were higher than the single pollutant models.
郑山, 王敏珍, 王式功, 陶燕, 尚可政. 大气污染物对兰州心脑血管疾病住院影响的病例交叉研究[J]. 中国环境科学, 2012, 32(7): 1182-1187.
ZHENG Shan, WANG Min-Zhen, WANG Shi-Gong, TAO Yan, SHANG Ke-Zheng. A case-crossover analysis of air pollution and hospital admissions for cardiovascular and cerebrovascular diseases in Lanzhou. CHINA ENVIRONMENTAL SCIENCECE, 2012, 32(7): 1182-1187.
