Abstract：Specific oxygen uptake rate (SOUR), respiratory inhibitory rate of activated sludge and light loss from luminous bacteria were used as indicators, biodegradability and acute toxicity of fosfomycin, α-phenylethylamine as well as their mixtures were investigated. The results showed that the acute toxicity and respiratory inhibitory rate of α-phenylethylamine were higher than those of fosfomycin. The biodegradability and acute toxicity of their mixtures highly depended on the ratios of α-phenylethylamine. For instance, biodegradability of the mixtures didn’t change when the ratio of α-phenylethylamine was lower than 25%. However, biodegradability of the mixtures decreased while the ratio of α-phenylethylamine exceeded 25%. The acute toxicity of the mixture was the lowest when the ratio of α-phenylethylamine was 25%.
