Abstract:The zebrafish embryos technology and traditional toxicology methods were used to determined the toxicity of fluopicolide to zebrafish embryos、adult fish and larvae. Fluopicolide had lethal capabilities to the three stages of zebrafish with the LC50(48h) values to larvae and LC50(96h) to adult fish and juvenile was 0.204mg/L, 0.286mg/L and 1.489mg/L. 0.0596mg/L or more concentrations fluopicolide have a certain degree of lethal effect to zebrafish embryos, and the embryos which were treated with high concentrations displayed many of the symptoms, such as pericardial cyst, yolk sac does not absorb, less melanin deposition and fish bending. After 14days exposure with fluopicolide, the adult zebrafishs expressed the following symptoms: weight loss, reduction in fecundity, the amount of effective eggs were reduced; After treated by 0.0298mg/L fluopicolide, though 144h offspring larval’s survival relatively high, but most surviving fish has still emerged as deformity: pericardial edema and abnormal body bending, etc. Fluopicolide residue in water have the potential hazards to the growth and development of each life stage of zebrafish.
林琎, 王红艳, 王开运, 范维娣, 许辉, 刘杰. 氟吡菌胺对斑马鱼的毒性效应[J]. 中国环境科学, 2014, 34(12): 3230-3236.
LIN Jin, WANG Hong-Yan, WANG Kai-Yun, FAN Wei-Di, XU Hui, LIU Jie. Toxic effects of fluopicolide on zebrafish. CHINA ENVIRONMENTAL SCIENCECE, 2014, 34(12): 3230-3236.