Abstract:To investigate the difference in the molecular mechanism of the genus Acidithiobacillus responding to extreme mine environment, two A. ferrooxidans strains, one A. caldus strain and one A. ferrivorans strain were analyzed in the diversity of two-component signal transduction systems (TCS) by using the bioinformatics method. The results showed that 27~38 TCS proteins were respectively identified from the four Acidithiobacillus strains. These TCS proteins were clustered into 16 paired groups, four groups of orphan histidine protein kinases, and nine groups of orphan response regulator proteins, demonstrating significant correlationship with their evolutionary branches. Among TCS proteins, nine groups of paired TCSs and five groups of non-paired TCSs were shared by the four strains of Acidithiobacillus, while the other TCSs were absent at least in one strain. Common TCS proteins of the four strains played basic biological roles including nitrogen fixation and citrate/malate metabolism regulation. Specific TCS proteins got involved in chemotaxis regulation, heavy metal response, and copper resistance regulation, which might contribute to survival of bacterial strains under the extreme mine environment.
余水静, 彭涛, 周丹, 潘涛, 董伟, 陈江安, 邱廷省. 嗜酸硫杆菌双组分信号转导系统多样性分析[J]. 中国环境科学, 2015, 35(7): 2146-2152.
YU Shui-Jing, PENG Tao, ZHOU Dan, PAN Tao, DONG Wei, CHEN Jiang-An, QIU Ting-Sheng. Diversity analysis of two-component signal transduction systems in the genus Acidithiobacillus. CHINA ENVIRONMENTAL SCIENCECE, 2015, 35(7): 2146-2152.