Determination and risk assessment of chloramphenicols in Panjiakou Reservoir, Hebei Province
LU Cheng1, ZHANG Jun2, WANG Zhao2, CAO Bi-Bo1, XU Ming-Xia2, WANG Yu-Qiu1
1. College of Environmental Science and Engineering, Nankai University, Tianjin 300071, China;
2. Haihe River Water Environmental Monitoring Centre, Tianjin 300170, China
Four chloramphenicols, including chloramphenicol, thiamphnicol, florfenicol and florfenicol amine, were investigated in the water from the Panjiakou Reservoir located in Hebei Province, by utilization of solid phase extraction-high performance liquid chromatography-tandem spectrometry (SPE-HPLC-MS/MS). Electrospray ionization and multiple reactions monitoring in positive or negative ionization mode were adopted as the target compounds for qualitative and quantitative analysis. The recoveries of target compounds were all above 90%, with the relative standard deviations (RSDs) ranged between 1.60% and 5.43%. The limits of detection (LODs) and limits of quantification (LOQs) for target compounds were in the range of 0.06~0.29ng/L and 0.18~0.87ng/L, respectively. The detected concentrations of florfenicol in the water samples were in the range of 26.21~233.35ng/L, and detected florfenicol amine were in the range 0.53~8.18ng/L. However, chloramphenicol and thiamphnicol were not detected in the water samples. Additionally, the risk assessments showed that the risk quotient (RQ) for detected antibiotics were below 1, which indicated very low risk to plankton and human health. The RQs of adult and child in wet season were over 100times higher than that in regular level, which might be caused by either the cage culture period or potential impact from water diversion in the reservoir.
卢诚, 张俊, 王钊, 曹碧波, 徐铭霞, 王玉秋. 河北潘家口水库氯霉素类抗生素检测及风险评估[J]. 中国环境科学, 2016, 36(6): 1843-1849.
LU Cheng, ZHANG Jun, WANG Zhao, CAO Bi-Bo, XU Ming-Xia, WANG Yu-Qiu. Determination and risk assessment of chloramphenicols in Panjiakou Reservoir, Hebei Province. CHINA ENVIRONMENTAL SCIENCECE, 2016, 36(6): 1843-1849.
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