Bioconcentration of organic UV filters in Carassius auratus and metabolic enzyme response
LU Guang-hua1, LI Sheng2, ZONG Yong-chen1, HUANG Yi1
1. College of Hydraulic and Civil Engineering, Xizang Agriculture and Animal Husbandry College, Linzhi 860000, China;
2. Key Laboratory of Integrated Regulation and Resources Development of Shallow Lakes, Ministry of Education, College of Environment, Hohai University, Nanjing 210098, China
The semi static exposure test was used to investigate the distribution and accumulation of organic UV filter 2-ethylhexyl 4-dimethylaminobenzoate (OD-PABA) in different tissues in Carassius auratus and to determine its ecotoxicological effects. The contents of OD-PABA in different tissues increased corresponding to the increasing exposure concentrations, and reached the maximum at day 14 or 28. The bioconcentration factor (BCF) of OD-PABA in different tissues obviously depended on the different exposure concentrations, and the BCF values calculated at day 14 and 28 were 123~186 in liver, 117~163 in skin and 90.2~147 in kidney, respectively. OD-PABA significantly induced EROD, PROD, BFCOD and GST activities in fish liver, EROD and GST activities showed more remarkable responses, and the maximum induction folds were 0.97 and 0.53, respectively. Our results suggest that OD-PABA in water can concentrate in Carassius auratus and be biotransformed by I phase and Ⅱ phase metabolic enzymes.
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