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Research progress on toxicological characteristics and mechanisms of urban atmospheric particulate matters |
Du Peng-rui, DU Rui, REN Wei-shan |
College of Resources and Environment, University of Chinese Academy of Sciences, Beijing 100049, China |
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Abstract Atmospheric particulate matters (PM) seriously affect the human health and the strong exposure-response relationship between PM and many human diseases has been confirmed. In this paper, the components and sources of particulate matter were briefly introduced and the harms to human health were systematically summarized on the aspects of respiratory toxicity, cardiovascular toxicity, immune toxicity, neurotoxicity, and genotoxicity. Additionally, the mechanisms of toxicity of particulate matter were summarized and discussed. We also pointed out the problems in the current study and the trends of future research. It will be contributable to the control of atmospheric particle pollution and provide the appropriate scientific reference for the studies on toxicological mechanisms of PM health damage.
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Received: 26 December 2015
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