|
|
|
| Thermochemical mechanism of the interaction between sulfamethazine antibiotics and extracellular polymers |
| WANG Jing1, ZHANG Cheng-cheng2, JI Fang-ying2, YAN Peng3 |
1. Department of Traffic and Municipal Engineering, Chongqing Jianzhu College, Chongqing 400072, China;
2. Key Laboratory of the Three Gorges Reservoir Region's Eco-Environments, Ministry of Education, Chongqing University, Chongqing 400045, China;
3. Chongqing Institute of Green and Intelligent Technology, Chinese Academy of Sciences, Chongqing 400714, China |
|
|
|
|
Abstract Thermodynamic parameters of interactions between extracelluar polymeric substances (EPS) and sulfamethazine antibiotics were investigated by isothermal titration calorimetry (ITC) in this study. Results showed that extracellular proteins strongly combined with sulfamethazine (SMZ), and the binding process depended on entropy driven by the hydrophobic interaction as the main driving force. The binding was significantly affected by pH and ionic strength. The binding of EPS and SMZ and the conformational change was the most favorable and the maximal, respectively, at the condition of pH 6.8. The ionic strength had a significant effect on the interaction between EPS and SMZ. The results implied that EPS contained in activated sludge may had a significant influence on the fate of antibiotics in water environment.
|
|
Received: 30 March 2017
|
|
|
|
|
|
| [1] |
Thiele-Bruhn S. Pharmaceutical antibiotic compounds in soils a review[J]. Journal of Plant Nutrition and Soil Science, 2003,166:145-167.
|
| [2] |
Zhou Q, PENG D P, Wang Y L, et al. A novel hapten and monoclonal-based enzyme-linked immunosorbent assay for sulfonamides in edible animal tissues[J]. Food Chemistry, 2014,154:52-62.
|
| [3] |
Chen Y S, Schwack W. Rapid and selective determination of multi-sulfonamides by high-performance thin layer chromatography coupled to fluorescent densitometry and electrospray ionization mass detection[J]. Journal of Chromatography A, 2014,1331:108-116.
|
| [4] |
Heberer T. Occurrence,fate,and removal of pharmaceutical residues in the aquatic environment:a review of re-cent research data[J]. Toxicology Letters, 2002,131:5-17.
|
| [5] |
赵健,杨晓凡,周福来,等.固相萃取/高效液相色谱/串联质谱法测定磺胺类抗生素[J]. 中国给水排水, 2012,28(14):98-101.
|
| [6] |
Badireddy A R, Chellam S, Gassman P L, et al. Role of extracellular polymeric substances in bioflocculation of activated sludge microorganisms under glucose-controlled conditions[J]. Water Research, 2010,44:4505-4516.
|
| [7] |
Ueshima M, Ginn Brian R, Haack Elizabeth A, et al. Cd adsorption onto Pseudomonas putida in the presence and absence of extracellular polymeric substances[J]. Geochimica Et Cosmochimica Acta, 2008,72:5885-5895.
|
| [8] |
Guibaud G, Comte S, Bordas F, et al. Comparison of the complexation potential of extracellular polymeric substances (EPS), extracted from activated sludges and produced by pure bacteria strains, for cadmium, lead and nickel[J]. Chemosphere, 2005,59:629-638.
|
| [9] |
D'Abzac P, Bordas F, Van Hullebusch E, et al. Effects of extraction procedures on metal binding properties of extracellular polymeric substances (EPS) from anaerobic granular sludges[J]. Colloids and Surfaces B-Biointerfaces, 2010,80:161-168.
|
| [10] |
Martin J, Camacho-Munoz D, Santos J, et al. Occurrence of pharmaceutical compounds in wastewater and sludge from wastewater treatment plants:Removal and ecotoxicological impact of wastewater discharges and sludge disposal[J]. Journal of Hazardous Materials, 2012,239:40-47.
|
| [11] |
Radjenovic J, Petrovic M, Barcelo D. Fate and distribution of pharmaceuticals in wastewater and sewage sludge of the conventional activated sludge (CAS) and advanced membrane bioreactor (MBR) treatment[J]. Water Research, 2009,43(3):831-841.
|
| [12] |
Xu J, Sheng G P, Ma Y, et al. Roles of extracellular polymeric substances (EPS) in the migration and removal of sulfamethazine in activated sludge system[J]. Water Research, 2013,47:5298-5306.
|
| [13] |
周洁,玉延华,胡炜,等.圆二色与等温滴定微量热技术检测3种微量元素与人血清白蛋白的结合[J]. 基因组学与应用生物学, 2014,33(2):413-417.
|
| [14] |
Frank B P, Belfort G. Polysaccharides and sticky membrane surfaces:critical ionic effects[J]. Journal of Membrane Science, 2003,212:205-212.
|
| [15] |
Ye Y, Le Clech P, Chen V, et al. Fouling mechanisms of alginate solutions as model extracellular polymeric substances[J]. Desalination, 2004,175:7-20.
|
| [16] |
Priyananda P, Chen V. Flux decline during ultrafiltration of protein-fatty acid mixture[J]. Journal of Membrane Science, 2006,273:58-67.
|
| [17] |
Mrinmoy D, YOU C C, Srivastava S, et al.Biomimetic interactions of proteins with functionalized nanoparticles:A thermodynamic study[J]. Journal of the American Chemical Society, 2007,129:10747-10753.
|
| [18] |
Xu J, Sheng G P, Ma Y, et al. Roles of extracellular polymeric substances (EPS) in the migration and removal of sulfamethazine in activated sludge system[J]. Water Research, 2013,47:5298-5306.
|
| [19] |
Ross P D, Subramabian S. Thermodynamics of protein association reactions-forces contributing to stability[J]. Biochemistry, 1981,20:3096-3102.
|
|
|
|
