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Research advances on the cytotoxic effects of zero-dimensional carbon-based nanomaterials |
LI Yi-meng1, LIU Xi2, WU Tian-shu1 |
1. The Key Laboratory of Environmental Medicine Engineering, School of Public Health, Southeast University, Nanjing 210009, China; 2. School of Medicine, Southeast University, Nanjing 210009, China |
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Abstract The main pathways of carbon-based nanomaterials entering into cells were introduced in this paper, and the analysis of different forms of cell death caused by several commonly used zero-dimensional carbon-based nanomaterials and their potential toxic mechanisms was focused on. The physical and chemical factors affecting the cell death induced by carbon-based nanomaterials were elaborated as well. Finally, the prospects of toxicity study of carbon-based nanomaterials based on our findings were provided in this review, which benefits the design optimization and wider application of carbon-based nanomaterials in the future.
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Received: 28 January 2021
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