1. College of Environment and Ecology, Chongqing University, Chongqing 400044, China; 2. Key Laboratory of Eco-environments in Three Gorges Reservoir Region, Ministry of Education, Chongqing 400044, China
摘要 Through literature collection, study and bibliometric analysis of Citespace literature, this paper summarizes the development history of mass spectrometry imaging (MSI) technology and its latest application status in the environmental field. Combined with the current research bottleneck in the environmental field, the development prospect of MSI is deeply discussed. MSI, as a new technology integrating high sensitivity mass spectrometry and high precision spatial resolution imaging, can directly collect and identify molecular information from the sample. In the field of environmental toxicology and monitoring, MSI, on one hand, can demonstrate the distribution, location and quantify the pollutants and their transformed products in environmental media or within biological tissues, cells and even sub-cells, and thus reveal the target of pollutant action. On the other hand, it can analyse the characteristics and mechanisms of pollutants' bioaccumulation, biotransformation and metabolic activation. In summary, the application of MSI in the environmental field has important scientific significance, providing a new perspective in the monitoring of water, air and soil pollution, particularly for in situ identification of pollutants and analysis of their toxic effects. Besides, it provides a scientific basis for the risk screening, assessment and control of pollutants.
Abstract：Through literature collection, study and bibliometric analysis of Citespace literature, this paper summarizes the development history of mass spectrometry imaging (MSI) technology and its latest application status in the environmental field. Combined with the current research bottleneck in the environmental field, the development prospect of MSI is deeply discussed. MSI, as a new technology integrating high sensitivity mass spectrometry and high precision spatial resolution imaging, can directly collect and identify molecular information from the sample. In the field of environmental toxicology and monitoring, MSI, on one hand, can demonstrate the distribution, location and quantify the pollutants and their transformed products in environmental media or within biological tissues, cells and even sub-cells, and thus reveal the target of pollutant action. On the other hand, it can analyse the characteristics and mechanisms of pollutants' bioaccumulation, biotransformation and metabolic activation. In summary, the application of MSI in the environmental field has important scientific significance, providing a new perspective in the monitoring of water, air and soil pollution, particularly for in situ identification of pollutants and analysis of their toxic effects. Besides, it provides a scientific basis for the risk screening, assessment and control of pollutants.
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