珠三角河流饮用水源中皮质激素的污染与风险

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摘要利用固相萃取联合液相色谱-质谱法对珠三角河流饮用水源中的21种糖皮质激素（GCs）和3种盐皮质激素（MCs）进行了研究.结果发现，24种目标物在水源水中均有检出，检出率在8%（可的松）~75%（地夫可特）之间，总浓度（∑CSs）（平均值/中值）为0.29~8.7ng/L（2.6ng/L/1.6ng/L），污染以布地奈德、丙酸氯倍他索、醛固酮为主.东江东莞段和流溪河下游水源水中肾上腺皮质激素（CSs）浓度水平总体高于西江和北江，各水源地的CSs组成与浓度存在一定的季节性差异.冗余分析发现，水源水中大部分CSs与水温、电导率、pH值以及溶解氧呈负相关关系，表明这些环境因子是影响CSs含量分布的重要因素.CSs在珠三角河流水源地的危害指数（HI）（平均值/中值）在<0.1~0.65（0.25/0.29）之间，总体处于中低风险水平.

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关键词 ：皮质激素, 饮用水源, 内分泌干扰物, 珠江三角洲

Abstract：The occurrence and eco-risks of typical corticosteroids (CSs) including 21 glucocorticoids and 3 mineralocorticoids were studied in the drinking water sources of the rivers from the Pearl River Delta. The solid phase extraction and liquid chromatography-mass spectrometry were employed. The 24 target compounds were all detected in the source water samples. Their detection frequencies ranged from 8% (cortisone) to 75% (deflazacort), and the total concentrations (∑CSs) were in a range (mean/median) of 0.29~8.7ng/L (2.6ng/L/1.6ng/L). Budesonide, clobetasol propionate and aldosterone were the major pollutants. The concentrations of CSs in the source water from the Dongjiang River and lower reach of the Liuxi River were generally higher than those of the Xijiang River and Beijiang River. Besides the CS compositions and concentrations varied seasonally from river to river. Redundancy analysis showed that most of CSs in the source water were negatively correlated with water temperature, conductivity, pH, and dissolved oxygen, suggesting that the occurrence and distribution of CSs in the source water can be influenced by these environmental factors. Moreover, the hazard index (HI) of CSs in the water sources of the Pearl River Delta ranged from <0.1to 0.65 (mean/median:0.25/0.29), indicating that low and medium risks were present in these waters.

Key words： corticosteroids drinking water source endocrine disrupting chemicals Pearl River Delta

收稿日期: 2019-04-18

PACS:

X522

基金资助:国家自然科学基金资助面上项目（41673110）；广州市科技计划项目（201607010217）

通讯作者: 龚剑,副研究员,gong_jian@mails.ucas.ac.cn E-mail: gong_jian@mails.ucas.ac.cn

作者简介: 林粲源(1994-),男,广东广州人,广州大学硕士研究生,主要从事内分泌干扰物的水陆环境行为、风险研究.发表论文3篇.

引用本文:

林粲源, 龚剑, 熊小萍, 周永顺, 吴翠琴. 珠三角河流饮用水源中皮质激素的污染与风险[J]. 中国环境科学, 2019, 39(11): 4752-4761. LIN Can-yuan, GONG Jian, XIONG Xiao-ping, ZHOU Yong-shun, WU Cui-qin. Occurrence and risks of typical corticosteroids in drinking water sources of the rivers from the Pearl River Delta. CHINA ENVIRONMENTAL SCIENCECE, 2019, 39(11): 4752-4761.

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http://www.zghjkx.com.cn/CN/ 或 http://www.zghjkx.com.cn/CN/Y2019/V39/I11/4752

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