We analyzed the spatial distribution and temporal variation trend of tropospheric NO2 over Guangdong-Hong Kong-Macao Greater Bay Area (GBA) using the satellite retrieved data from the Ozone Monitoring Instrument (OMI) sensor, and the influencing factors for these temporal-spatial characteristics. The results showed that the tropospheric NO2 decreased by about 2.8% per year from 2005 to 2018 over GBA. The wavelet coefficients showed that there was a 9 months of main oscillation period and the higher and lower concentration appeared in winter and summer, respectively. Due to the effects of anthropogenic emissions and various natural factors, the monthly variation of the tropospheric NO2 was significantly different in time and space over GBA. The minimum and maximum values appeared in June and December, respectively, and the multi-years mean values were 3.9665×1015 and 12.3423×1015 molec/cm2. The tropospheric NO2 showed obvious spatial heterogeneity characteristics, the most obvious heterogeneity was in December. The high-value areas with serious NO2 pollution over GBA were mainly found in the central region, such as Guangzhou, Foshan and Zhongshan cities. The maximum tropospheric NO2 column density was up to 18.8306×1015molec/cm2. It was about three times that of the surrounding areas, and the high-pollution gradually extended around areas. The low-value areas were mainly in northern Zhaoqing City and eastern Huizhou City, and the average tropospheric NO2 concentration was about 7.1400×1015molec/cm2. The growth rates showed a significant difference over GBA. The tropospheric NO2 column density varies from -15×1015 to 6×1015molec/cm2, and the growth rates from -65% to 65%. The increased areas occurred in northern Zhaoqing City and the eastern Huizhou city. The larger reduced were concentrated in the high value areas in the middle, and the largest reduced were the junction of Guangzhou City, Foshan City and Zhongshan City.
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