Abstract：Nano-particles (NPs) such as nano-silica, nano-carbon powder, nano-zinc oxide, nano-cerium oxide, nano-silicon carbide and nano-iron tetroxide were used as representatives to study their effects on the interface properties of pulmonary surfactant (PS). The results shown that NPs had adsorption effects on both phospholipid and protein components in PS, and nano-silica and nano-ferric tetroxide had the strongest adsorption capacity for phospholipid and protein components, respectively, with adsorption rates of 89.3% and 82.5%. The existence of NPs would lead to the increase of the surface tension of PS solution, among which the effect of nano-silica was the most significant. Particles such as nano-silicon carbide and nano-silicon dioxide can cause the inward shrinkage/outward expansion of the π-A isotherm of the PS film, and the higher the particle concentration, the more obvious the surface pressure change. In addition, PS also had an effect on the hydration kinetic diameter and Zeta potential of NPs, resulting in the change of its dispersion state. It can be seen that NPs can change the composition and interface of PS by changing the composition and interface of PS.
刘丹, 李杰, 曹妍, 耿迎雪, 柴小龙, 蒋凡殊, 师伟萌, 赵群, 田森林. 纳米颗粒物对肺表面活性物质界面性质的影响[J]. 中国环境科学, 2022, 42(5): 2379-2386.
LIU Dan, LI Jie, CAO Yan, GENG Ying-xue, CHAI Xiao-long, JIANG Fan-shu, SHI Wei-meng, ZHAO Qun, TIAN Sen-lin. Effect of nano-particles on interfacial chemical properties of pulmonary surfactant. CHINA ENVIRONMENTAL SCIENCECE, 2022, 42(5): 2379-2386.
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