Pollution fromlivestock breeding is a key emphasis of pollution control ofChina. Ecological compensation policy has great significance both in encouraging farmers to change traditional breeding mode andin reducing pollutant emissions.Using Jiuzhou River Basin as a case study, this paper set up a space optimization model for ecological compensation of pig-breedingbasedon large-scale survey data and related documents. The modeltook minimum amount of ecological compensationasthe objective, constrained by the capacity of water environmental capacity and cultivated landcarryingvapacity, at the same time ensuring nodeclinein the economic incomefrompig-breeding. The results showed that the minimum amount of ecological compensation in Jiuzhou River Basin is 583 million yuan, of which 292 million yuan is used for prohibitingthebreedingofabout 554 thousandpig-breeding, 194 million yuan is used to build environmentally-friendly breedinghouses insuitable area whichcanaccommodate the breeding of 479 thousand pigs, 97 million yuanis used for the transformation of breeding mode which about 185 thousands. After the optimization, the reduction of COD, TN and TP in the Jiuzhou River Basin would be 13980 t, 2545 t and 995 t.The total scale of livestock cultivation in the whole basin would be 1.2 million, with no traditionallivestock breeding modeand 81.19% using an environmentally-friendly model. There is a significant difference between the 10 towns both in compensation amount and pollutant reduction.Those towns with high compensation amounts are Wendi, Liangtian and Gucheng, accounting for 56.78% of the total compensation funds, and the COD reduction accounts for 55.35% of the total reduction. Through the optimized compensation plan, both environmental benefits and economic benefits can be achieved at the same time.