Thermochemical mechanism of the interaction between sulfamethazine antibiotics and extracellular polymers
WANG Jing1, ZHANG Cheng-cheng2, JI Fang-ying2, YAN Peng3
1. Department of Traffic and Municipal Engineering, Chongqing Jianzhu College, Chongqing 400072, China;
2. Key Laboratory of the Three Gorges Reservoir Region's Eco-Environments, Ministry of Education, Chongqing University, Chongqing 400045, China;
3. Chongqing Institute of Green and Intelligent Technology, Chinese Academy of Sciences, Chongqing 400714, China
Thermodynamic parameters of interactions between extracelluar polymeric substances (EPS) and sulfamethazine antibiotics were investigated by isothermal titration calorimetry (ITC) in this study. Results showed that extracellular proteins strongly combined with sulfamethazine (SMZ), and the binding process depended on entropy driven by the hydrophobic interaction as the main driving force. The binding was significantly affected by pH and ionic strength. The binding of EPS and SMZ and the conformational change was the most favorable and the maximal, respectively, at the condition of pH 6.8. The ionic strength had a significant effect on the interaction between EPS and SMZ. The results implied that EPS contained in activated sludge may had a significant influence on the fate of antibiotics in water environment.
王静, 张程程, 吉芳英, 晏鹏. 磺胺类抗生素与胞外聚合物作用的热化学机制[J]. 中国环境科学, 2017, 37(10): 3758-3763.
WANG Jing, ZHANG Cheng-cheng, JI Fang-ying, YAN Peng. Thermochemical mechanism of the interaction between sulfamethazine antibiotics and extracellular polymers. CHINA ENVIRONMENTAL SCIENCECE, 2017, 37(10): 3758-3763.
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