Influence factors controlling fluorine bioaccessibility in contaminated soils and corresponding health risks
LI Hui1,2, HAN Zhan-tao3, LIU Xin-bu4, WANG Yan-yan1,2, ZHANG Wei1,2, MA Li-sha1,2
1. Institute of Hydrogeology and Environmental Geology, Chinese Academy of Geological Sciences, Shijiazhuang 050061, China; 2. Key Laboratory of Groundwater Contamination and Remediation of Hebei Province and China Geological Survey, Shijiazhuang 050061, China; 3. Technical Centre for Soil, Agriculture and Rural Ecology and Environment, Ministry of Ecology and Environment, Beijing 100012, China; 4. Hebei Geology University, Shijiazhuang 050031, China
Abstract：Fluorine (F) bioaccessibility of 16 soil samples from a contaminated site of Taiyuan was measured using the method of in vitro of gastrointestinal digestion, and the influence of F bioaccessibility on its risk assessment was evaluated. The results revealed that F bioaccessibility in the stomach and intestine were between 2.59%~6.57% and 1.09~2.52,with the average value of 3.53% and 1.44%, respectively. F bioaccessible concentration in stomach was positive correlated with water soluble F (cs') (P<0.01,n=16), total Fe (TFe) (P<0.01,n=16) and total Al (TAl) (P<0.01,n=16) in soils, while F bioaccessible concentration in intestine was positive correlated with that in stomach (P<0.01,n=16). A model regressed based on cs' and TAl in the soil could predict F bioaccessibility in the stomach very well with R2 being 0.96, and the bioaccessibility in the intestine could be predicted precisely using a regression model based on that in the stomach with R2 being 0.98. The health risk calculated based on F concentration in the soils was 15.23~37.01times and 39.76~86.67 times the values when the bioaccessibility in the stomach and intestine were considered in calculation.
李卉, 韩占涛, 刘心哺, 王妍妍, 张威, 马丽莎. 污染土壤中氟的人体胃肠吸收可给性影响因素及健康风险[J]. 中国环境科学, 2021, 41(2): 951-958.
LI Hui, HAN Zhan-tao, LIU Xin-bu, WANG Yan-yan, ZHANG Wei, MA Li-sha. Influence factors controlling fluorine bioaccessibility in contaminated soils and corresponding health risks. CHINA ENVIRONMENTAL SCIENCECE, 2021, 41(2): 951-958.
杨金燕,苟敏.中国土壤氟污染研究现状[J]. 生态环境学报, 2017,26(3):506-513.Yang J Y, Gou M. The research status of fluorine contamination in soil of China[J]. Ecology and Environmental Sciences, 2017,26(3):506-513.
[2]
章萍,杨陈凯,马若男,等.碳纳米管/羟基磷灰石复合材料对水体F- 的去除研究[J]. 中国环境科学, 2019,39(1):179-187.Zhang P, Yang C K, Ma R N, et al. Effective removal pf fluoride by carbon nanotubes/hydroxyapatite compasites[J]. China Environmental Science, 2019,39(1):179-187.
[3]
Zhang L, Huang D, Yang J, et al. Probabilistic risk assessment of Chinese residents' exposure to fluoride in improved drinking water in endemic fluorosis areas[J]. Environmental Pollution, 2017,222:118-125.
[4]
李随民,栾文楼,韩腾飞,等.冀中南平原区土壤氟元素来源分析[J]. 中国地质, 2012,39(3):794-803.Li S M, Luan W L, Han T F, et al. A source analysis of soil fluorine in central and southern Hebei plain[J]. Geology in China, 2012,39(3):794-803.
[5]
Paul A G, Jones K C, Sweetman A J. A first global production, emission, and environmental inventory for perfluoroctane sulfonate[J]. Environmental Science and Technology, 2009,43(2):386-392.
[6]
HJ25.3-2014污染场地环境风险评估技术导则[S]. HJ25.3-2014 Technical guidelines for risk assessment of contaminated sites[S].
[7]
Broadway A, Cave M R, Wragg J, et al. Determination of the bioaccessibility of chromium in Glasgow soil and the implications for human health risk assessment[J]. Science of the Total Environment, 2010,409(2):267-277.
[8]
Chabukdhara M, Nema A K. Heavy metals assessment in urban soil around industrial clusters in Ghaziabad, India:Probabilistic health risk approach[J]. Ecotoxicology and Environmental Safety, 2013,87(1):57-64.
[9]
钟茂生,彭超,姜林,等.污染场地土壤中Cd人体可给性影响因素及对筛选值的影响[J]. 中国环境科学, 2015,35(7):2217-2224.Zhong M S, Peng C, Jiang L, et al. Factors controlling bioaccessibility of Cd in soil from contaminated sites and its implication on soil screening values[J]. China Environmental Science, 2015,35(7):2217-2224.
[10]
Tang X, Zhu Y, Shan X, et al. The effect of ageing on the bioaccessibility and fractionation of arsenic in soils from China[J]. Chemosphere, 2007,66(7):1183-1190.
[11]
徐瑾,陈广春,何欢,等.应用体外胃肠模拟法研究土壤中多氯联苯的生物有效性[J]. 环境化学, 2011,30(5):908-912.Xu J, Chen G C, He H, et al. Investigationon the bioaccessibility of PCBs in soils using an gastrointestinal model[J]. Environmental Chemistry, 2011,30(5):908-912.
[12]
Tao S, Lu Y, Zhang D Y, et al. Assessment of oral bioaccessibility of organochlorine pesticides in soil using an in vitro gastrointestinal model[J]. Environmental Science Technology, 2009,43(12):4524-4529.
[13]
Intawongse M, Dean J R. Use of the physiologically-based extraction test to assess the oral bioaccessibility of metals in vegetable plants grown in contaminated soil[J]. Environmental Pollution, 2008,152(1):60-72.
[14]
付瑾,崔岩山.食物中营养物及污染物的生物可给性研究进[J]. 生态毒理学报, 2011,6(2):113-120.Fu J, Huo Y S. Advance in bioaccessibility of nutrients and pollutants in food[J]. Asian Journal of Ecotoxicology, 2011,6(2):113-120.
[15]
Ruby M V, Schoof R, Brattin W, et al. Advances in evaluating the oral bioavailability of inorganics in soil for use in human health risk assessment[J]. Environmental Science and Technology, 1999,33(21):3697-3705.
[16]
Agnieszka E, Pete R, Brian J. Decision-makers' perspectives on the use of bioaccessibility for risk-based regulation of contaminated land[J]. Environment International, 2010,36(4):383-389.
[17]
Wragg J, Cave M. In-vitro methods for the measurement of the oral bioaccessibility of selected metals and metalloids in soils:a critical review[R]. Nottingham:British Geological Survey, 2002.
[18]
尚德容,赵宪勇,宁劲松,等.应用体外仿生模型分析南极磷虾中氟的生物可给性及其对人体的健康风险[J]. 中国渔业质量与标准, 2014,4(4):21-26.Shang D R, Zhao X Y, Ning J S, et al. Bioaccessibility analysis and health risk assessment of fluorine in Euphausia superba using in vitro whole-bionic model[J]. Chinese Fishery Quality and Standards. 2014, 4(4):21-26.
[19]
HJ873-2017土壤水溶性氟化物和总氟化物的测定离子选择电极法[S].HJ873-2017 Soil-determination of water soluble fluoride and total fluoride -Ion seletive method[S].
[20]
Ljung K, Oomen A G, Duits M, et al. Bioaccessibility of metals in urban playground soils[J]. J Environmental Science and Health, Part A, 2007,42(9):1241-1250.
[21]
Pelfrene A, Waterlot C, Mazzuca M, et al. Assessing Cd, Pb, Zn human bioaccessibility in smelter contaminated agricultural topsoils (northern France)[J]. Environmental Geochemistry Health, 2011,33(5):477-493.
[22]
Wragg J, Cave M, Taylor R H, et al. Interlaboratory trial of a unified bioaccessibility procedure[R]. Nottingham:British Geological Survey, 2009.
[23]
Miller D D, Schricker B R, Rasmussen R R, et al. An in vitro method for estimation of iron availability from meals[J]. American Journal of Clinical Nutrition, 1981,34(10):2248-2256.
[24]
钟茂生,彭超,姜林,等.老化土壤中As的人体可给性控制因素及健康风险[J]. 环境科学研究, 2015,28(2):267-274.Factors controlling arsenic bioaccessibility in aged soil and corresponding health risks[J]. Research of Environmental Sciences, 2015,28(2):267-274.
[25]
崔岩山,陈晓晨.土壤中镉的生物可给性及其对人体的健康风险评估[J]. 环境科学, 2010,31(2):403-408.Cui Y S, Chen X C. Bioaccessibility of soil cadmium and its health risk assessment[J]. Environmental Science, 2010,31(2):403-408.
[26]
陆俊,敦惠瑜,向孝哲,等.体外模拟胃、肠消化对6种黑色食品抗氧化成分及其活性的影响[J]. 食品科学, 2018,39(5):47-56.Lu J, Dun H Y, Xiang X Z, et al. Effect of in vitro simulated gastrointesinal digestion on bioactive components and antioxidant activities of six kinds of black foods[J]. Food Science, 2018,39(5):47-56.
[27]
于群英,李孝良,汪建飞,等.安徽省土壤氟含量及其赋存特征[J]. 长江流域资源与环境, 2013,22(7):915-921.Yu Q Y, Li X L, Wang J F, et al. Content of fluorine and characteristics of fluorine from in soil of Anhui Province[J]. Resources and Environment in the Yangtze Basin, 2013,22(7):915-921.
[28]
Farooq I, Ali S, Al-Khalifa K S, et al. Total and soluble fluoride concentration present in various commercial brands of children toothpastes available in Saudi Arabia-A pilot study[J]. The Saudi Dental Journal, 2018,30(2):161-165.
[29]
夏静芬,傅建斌,罗春林.茶园土壤水溶性氟与全氟和pH值的相关性研究[J]. 广东微量元素科学, 2009,16(2):41-45.Xia J F, Fu J B, Luo C L.Correlation research between water soluble fluorine, total fluorine and pH value of tea-plating soil[J]. Guangdong Trace Elements Science, 2009,16(2):41-45.
[30]
余大富,胡延吉.土壤氟背景与人体氟效应[J]. 重庆环境科学, 1990,12(3):22-25.Yu D F, Hu Y J. The correlations beteen the contents of different forms of fluoride in soil and the fluorine-effects in human body[J]. Chongqing Environmental Science, 1990,12(3):22-25.
[31]
Sajil Kumar P J, Jegathambal P, Nair S, et al. Temperature and pH dependent geochemical modeling of fluoride mobilization in the groundwater of a crystalline aquifer in southern India[J]. Journal of Geochemical Exploration, 2015,156:1-9.
[32]
孔梦园,平建华,钟华平.高氟浅层地下水的水化学和分布特征实例分析[J]. 水利科技与经济, 2016,22(12):18-21.Kong M Y, Ping J H, Zhong H P. Case study hydrochemical and distributional features of shallow groundwater wit high concentration of fluorine[J]. Water Conservancy Science Thchnology and Economy, 2016,22(12):18-21.
[33]
谢美.氟与聚合羟基铝(铁)-蒙脱石复合体相互作用机理及土壤环境意义[D]. 青岛:中国海洋大学, 2005.Xie M. Interactions of fluoride with hyAl(Fe)-montmorillonite complexes and their implications for fluoride-contaminated acidic soils[J]. Qingdao:Qcean University of China, 2005.
[34]
Shu W S, Zhang Z Q, Lan C Y, et al. Fluoride and aluminium concentrations of tea plants and tea products from Sichuan Province, PR China[J]. Chemosphere, 2003,52(9):1475-1482.
[35]
Lung S C C, Hsiao P K, Chiang K M. Fluoride concentrations in three types of commercially packed drinks in Taiwan[J]. Journal of Exposure Analysis and Environmental Epidemiology, 2013,13:66-73.
