全氟辛酸在紫贻贝体内的富集、分布与消除

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摘要以紫贻贝为受试生物，采用半静态暴露的方式，研究了全氟辛酸（PFOA）在紫贻贝体内的富集特征、器官分布与消除规律.结果表明，紫贻贝可快速富集PFOA，整贝在不同浓度PFOA暴露下，于4~6d达到平衡态，半衰期为0.34~0.44d（约8~10h），生物富集系数（BCFs）为5.10~9.55mL/g.PFOA在紫贻贝鳃和内脏团中的富集作用大于外套膜、性腺和闭壳肌.紫贻贝中PFOA的含量在净化6~9d后趋于空白组水平，主要代谢途径可能为鳃的作用.紫贻贝对PFOA的富集作用与暴露浓度相关，浓度越低，吸收系数和生物富集系数越大.

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	崔文杰
	刘晓玉
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	谭志军
	李兆新
	郭萌萌
	翟毓秀

关键词 ：全氟辛酸(PFOA), 紫贻贝, 生物富集, 组织分布, 消除

Abstract：The accumulation characteristics, tissue distributions and elimination pathways of perfluorooctanoic acid (PFOA) in the mussels (Mytilus galloprpvincialis) were investigated. PFOA could be accumulated rapidly by the mussels, leading to the whole-body mussels reached steady-state after 4~6d exposure to different target concentrations. The half-lives of the whole-body mussel were 0.34~0.44d (about 8~10h) with the bioconcentration factors (BCFs) ranged from 5.10 to 9.55mL/g. PFOA tended to accumulate in gills and visceral mass. The concentrations of PFOA in mussels tended to be blank level after 6~9d of depuration and the main elimination pathway may by the gills. Moreover, the bioconcentration effect of PFOA in Mytilus galloprpvincialis was related to the exposure concentrations.

Key words： perfluorooctanoic acid (PFOA) Mytilus galloprpvincialis accumulation tissue distribution elimination

收稿日期: 2020-03-27

PACS:

X503.225

基金资助:国家重点研发计划项目（2017YFC1600705）；国家自然科学基金项目（41906130）；中国水产科学研究院基本科研业务费项目（2020TD71）；国家市场监督管理总局技术保障项目（2020YJ027）

通讯作者: 郭萌萌,高级工程师,guomm@ysfri.ac.cn;翟毓秀,研究员,zhaiyx@ysfri.ac.cn E-mail: guomm@ysfri.ac.cn;zhaiyx@ysfri.ac.cn

作者简介: 崔文杰(1995-),女,山东青岛人,中国海洋大学硕士研究生,主要研究方向为有机污染物安全检测与评价.

引用本文:

崔文杰, 刘晓玉, 孙晓杰, 谭志军, 李兆新, 郭萌萌, 翟毓秀. 全氟辛酸在紫贻贝体内的富集、分布与消除[J]. 中国环境科学, 2020, 40(9): 4091-4098. CUI Wen-jie, LIU Xiao-yu, SUN Xiao-jie, TAN Zhi-jun, LI Zhao-xin, GUO Meng-meng, ZHAI Yu-xiu. Accumulation, distribution and elimination of perfluorooctanoic acid (PFOA) in mussels (Mytilus galloprpvincialis). CHINA ENVIRONMENTAL SCIENCECE, 2020, 40(9): 4091-4098.

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