Interactive effects of polystyrene microplastics and bisphenol A on bioaccumulation and oxidative stress in the Yellow River carp (Cyprinus carpio haematopterus)
HOU Chen-li1,2, YU Yue1,2, YU Ling-hong1,2, WANG Zhi-chao1,2, YU Sheng-qian1,2, LI Wei-ping1,2
1. School of Energy and Environment, Inner Mongolia University of Science and Technology, Baotou 014010, China; 2. Collaborative Innovation Center of Autonomous Region for Ecological Protection and Comprehensive Utilization in the Inner Mongolia Section of the Yellow River Basin, Baotou 014010, China
Abstract：The purpose of the present study was to elucidate the effects of MPs (microporous) on the distribution and bioaccumulation of BPA (bisphenol A) in fish as well as their interactive toxicological effects in fish. Yellow River carp (Cyprinus carpio haematopterus) was employed as the model organism. In this study, the tissues accumulation characteristics of PS-MPs and BPA, histopathology and antioxidant enzyme activities of Yellow River carp under the combined with (0.5µm) PS-MPs and BPA were analyzed. The enrichment of PS-MPs followed the order of gut (55.70%) >gill (31.53%)> brain (7.76%) >liver (5.01%) in various tissues of carp after 21days of exposure. Compared with BPA treatment, BPA concentrations of BPA+MP20treatment in gill, liver, gut and brain were increased by 4.28%, 1.66%, 2.06% and 4.85%, respectively, increased by 11.88%, 15.18%, 3.15% and 10.54% in BPA+MP100 treatments, respectively. The presence of PS-MPs significantly increased the accumulation of BPA in carp tissues, and the accumulation of BPA in tissues increased with the increase of the concentration of PS-MPs, and the accumulation of BPA in liver was more dependent on the concentration of PS-MPs. Compared with the control treatment, single BPA or MPs combined with BPA could cause different degrees of inflammatory cell infiltration in each tissue of carp, and induce the increase of superoxide dismutase (SOD), catalase (CAT), glutathione (GSH) activity and malondialdehyde (MAD) content in each tissue. However, interactive effects of BPA and high concentration of PS-MPs, the SOD and GSH activities in the intestine and liver of carp were induced to decrease the content of MAD, to mitigate the combined toxic effects of microplastics and bisphenol A on carp.
侯晨丽, 于越, 于玲红, 王志超, 于晟乾, 李卫平. 微塑料与双酚A联合下鲤鱼生物积累及氧化应激效应[J]. 中国环境科学, 2023, 43(8): 4334-4342.
HOU Chen-li, YU Yue, YU Ling-hong, WANG Zhi-chao, YU Sheng-qian, LI Wei-ping. Interactive effects of polystyrene microplastics and bisphenol A on bioaccumulation and oxidative stress in the Yellow River carp (Cyprinus carpio haematopterus). CHINA ENVIRONMENTAL SCIENCECE, 2023, 43(8): 4334-4342.
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