Influences of environmental substrates on microbial quorum-sensing signals
CHENG Yang-juan1,2, HUANG Dan1,2, WANG Yu-fan1,2, WANG Mei-zhen1,2
1. School of Environmental Science and Engineering, Zhejiang Gongshang University, Hangzhou 310012, China; 2. Zhejiang Provincial Key Laboratory of Solid Waste Treatment and Recycling, Hangzhou 310012, China
Abstract：Quorum sensing (QS) is a bacterial conversation mechanism that regulates free radical release, biofilm formation, and gene level transfer by releasing signaling molecules for intercellular communication. The media materials widely present in the environment can interact with signaling molecules and thus influence the behavior of microorganism populations. Although there are many reviews on QS signal molecules and their regulatory mechanisms, the effects of environmental substrates on intracellular and extracellular signal molecules have not been well synthesized. Therefore, this study aims to elucidate the structure-function relationships between signal molecules and environmental substrates by reviewing the physicochemical properties and biological functions of various signal molecules of microorganisms and evaluating the effects of environmental substrates, such as soil minerals, nanomaterials, biochar and natural small molecule compounds, on signal molecules, so as to provide a vital reference for the in-depth understanding of the QS regulation of microbial communities in a realistic environment.
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