PM<sub>10</sub>中重金属的健康风险评估及修正方法比较

摘要
图/表
参考文献
相关文章 (15)

全文: PDF (872 KB) HTML (1 KB)
输出: BibTeX | EndNote (RIS)

摘要通过对华南某电子垃圾拆解区PM₁₀中重金属含量特征分析，计算该地区的人群暴露量，评估人群健康风险，并引入靶器官毒性剂量法（TTD）和证据权重法（WOE）对常规评估方法的非致癌健康风险进行修正，比较探讨3种方法对非致癌健康风险评估结果的影响.结果表明：研究区域夏，冬季节的非致癌和致癌健康风险均为：儿童>成年女性>成年男性，重金属Ni对人群可能存在致癌风险（ILCR在10^-6~10^-4之间）.其中，Cr，Pb，Cd和As 4种重金属（类金属）对成年男性的非致癌健康风险值为3.05×10^-2，经TTD法和WOE法修正后为5.41×10^-2和5.4×10^-1，表明当综合考虑重金属作用的靶器官及重金属间的相互作用时，PM₁₀中重金属的非致癌健康风险值高于常规方法.

	服务

	把本文推荐给朋友
	加入我的书架
	加入引用管理器
	E-mail Alert
	RSS
	作者相关文章
	冯茜丹
	刘志磊
	陈启宇
	陈希超
	高梓旭
	王钰钰
	郑彤
	刘芸
	林必桂

关键词 ： PM₁₀, 重金属, 健康风险评估, 靶器官毒性剂量法, 证据权重法

Abstract：In this study, we characterized the content of heavy metals in PM₁₀, calculated the exposure levels for population and assessed the human health risks in an electronic waste dismantling area of South China. Subsequently, the non-carcinogenic health risks of the population were amended by the target organ toxic dose (TTD) method and weight of evidence (WOE) method, respectively. The results showed that the non-carcinogenic health risks in the summer and winter were:children > adult women > adult men, and the heavy metal Ni was probably carcinogenic risks to the population (ranged from 10^-6 to 10^-4). The non-carcinogenic health risk values of Cr, Pb, Cd and As for adult males were 3.05×10^-2 and the corrected risk values by the TTD and WOE methods were 5.41×10^-2 and 5.4×10^-1. Our results indicated that the assessment of non-carcinogenic health risk values of heavy metals from PM₁₀ should comprehensively consider the interactions between heavy metals.

Key words： PM₁₀ heavy metals health risk assessment target organ toxicity dose method evidence weight method

收稿日期: 2022-03-15

PACS:

X153

基金资助:中央级公益性科研院所基本科研业务专项（PM-zx703-202104-056，1630042021024）；国家重点研发计划项目（2019YFC1805504，2019YFC1805505）；国家自然科学基金青年科学基金资助项目（41105093）；广东省高等学校优秀青年教师培养计划项目（粤教师函[2014]145号）

通讯作者: 林必桂,高级工程师,linbigui@163.com E-mail: linbigui@163.com

作者简介: 冯茜丹(1980-),女,广东梅州人,副教授,博士,主要研究方向为环境污染健康风险评估.发表论文30篇.

引用本文:

冯茜丹, 刘志磊, 陈启宇, 陈希超, 高梓旭, 王钰钰, 郑彤, 刘芸, 林必桂. PM₁₀中重金属的健康风险评估及修正方法比较[J]. 中国环境科学, 2022, 42(10): 4880-4888. FENG Xi-dan, LIU Zhi-lei, CHEN Qi-yu, CHEN Xi-chao, GAO Zi-xu, WANG Yu-yu, ZHENG Tong, LIU Yun, LIN Bi-gui. Comparison of health risk assessment and correction methods of heavy metals in PM₁₀. CHINA ENVIRONMENTAL SCIENCECE, 2022, 42(10): 4880-4888.

链接本文:

http://www.zghjkx.com.cn/CN/ 或 http://www.zghjkx.com.cn/CN/Y2022/V42/I10/4880

[1]	Hu D, Jiang J.PM2.5 pollution and risk for lung cancer:A rising issue in China[J].Journal of Environmental Protection, 2014,5(8):731-738.
[2]	Liu Y, Hu J, Wang X, et al.Distribution, bioaccessibility, and health risk assessment of heavy metals in PM2.5 and PM10 during winter heating periods in five types of cities in Northeast China[J].Ecotoxicology Environmental Safety, 2021,214(11):124967-112071.
[3]	刘爱明,杨柳,吴亚玲,等.城市区域大气颗粒物的健康效应研究[J].中国环境监测, 2012,28(5):19-23.Liu A M, Yang L, Wu Y L, et al.Research on the health effects of atmospheric particulates in city region[J].Environmental Monitoring in China, 2012,28(5):19-23.
[4]	符小晴,彭晓武,王钰钰,等.广州市大气PM2.5中元素特征及重金属健康风险评价[J].环境与健康杂志, 2018,35(2):154-158.Fu X Q, Peng X W, Wang Y Y, et al.Characteristic of elements in PM2.5 and health risk assessment of heavy metals in Guangzhou[J].Journal of Environment and Health, 2018,35(2):154-158.
[5]	Charlesworth S, Miguel E D, Ordonez A.A review of the distribution of particulate trace elements in urban terrestrial environments and its application to considerations of risk[J].Environmental Geochemistry and Health, 2011,33(2):103-123.
[6]	何瑞东,张轶舜,陈永阳,等.郑州市某生活区大气PM2.5中重金属污染特征及生态健康风险评估[J].环境科学, 2019,40(11):4774-4782.He R D, Zhang Y S, Chen Y Y, et al.Heavy metal pollution characteristics and ecological and health risk assessment of atmospheric PM2.5 in a living area of Zhengzhou City[J].Environmental Science, 2019,40(11):4774-4782.
[7]	Sandrine C, David A, Sylvain B, et al.Origins and discrimination between local and regional atmospheric pollution in Haiphong (Vietnam), based on metal(loid) concentrations and lead isotopic ratios in PM10[J].Environmental Science and Pollution Research, 2018, 25(26):26653-26668.
[8]	Wilbur S B, Hansen H, Pohl H, et al.Using the ATSDR guidance manual for the assessment of joint toxic action of chemical mixtures[J].Environmental Toxicology Pharmacology, 2004,18(3):223-230.
[9]	ATSDR.Guidance manual for the assessment of joint toxic action of chemical mixtures[EB/OL].http://www.atsdr.cdc.gov/interactionprofiles/ipga.html.2018-10-12.
[10]	陈希超,朱晓辉,林必桂,等.华南某电子垃圾拆解区周边住宅室内灰尘重金属对儿童的非致癌健康风险评估[J].中华预防医学杂志, 2019,(4):360-364.Chen X C, Zhu X H, Lin B G, et al.Children's non-carcinogenic health risk assessment of heavy metals exposure to residential indoor dust around an e-waste dismantling area in South China[J].Chinese Journal of Preventive Medicine, 2019,53(4):360-364.
[11]	刘丽君,韩静磊,钱益斌,等.利用靶器官毒性剂量法(TTD)和证据权重分析法(WOE)评估固化飞灰中重金属非致癌健康风险[J].环境化学, 2019,38(5):1014-1020.Liu L J, Han J L, Qian Y B, et al.Assessment of heavy metal non-carcinogenic health risk in solidified fly ash using TTD and WOE methods[J].Environmental Chemistry Environ.Chem., 2019,38(5):1014-1020.
[12]	段宁,方丽婷,张湘泰.基于靶器官的土壤重金属非致癌健康风险评估[J].安全与环境工程, 2021,28(4):207-212.Duan N, Fang L T, Zhang X T.Non-carcinogenic health risk assessment of soil heavy metals based on target organs[J].Safety and Environmental Engineering, 2021,28(4):207-212.
[13]	Luo Y, Luo X J, Lin Z, et al.Polybrominated diphenyl ethers in road and farmland soils from an e-waste recycling region in Southern China:Concentrations, source profiles, and potential dispersion and deposition[J].Science of the Total Environment, 2009,407(3):1105-1113.
[14]	王珊珊,于瑞莲,胡恭任,等.厦门市大气PM2.5中重金属污染特征及健康风险评价[J].地球与环境, 2017,45(3):336-341.Wang S S, Yu R L, Hu G R, et al.Xiamen atmospheric PM2.5 pollution characteristics and health risk assessment of heavy metals[J].Earth and Environment, 2017,45(3):336-341.
[15]	Kurt-Karakus P B.Determination of heavy metals in indoor dust from Istanbul, Turkey:Estimation of the health risk[J].Environment International, 2012,50(50):47-55.
[16]	高梓旭,林必桂,韩雅静,等.珠三角电子垃圾拆解区积尘中重金属的赋存特征、生物可给性及健康风险[J].生态毒理学报, 2021,16(6):268-278.Gao Z X, Lin B G, Han Y J, et al.Characteristics, bioaccessibility and health risk of heavy metals bound-in dust in e-waste dismantling area of Pearl River Delta[J].Asian Jourmal of Ecotoxicology, 2021,16(6):268-278.
[17]	冯康宏,范缙,HII LIK UNG STANLEY,等.基于生物可给性的某冶炼厂土壤重金属健康风险评价[J].中国环境科学, 2021,41(1):442-450.Feng K H, Fang J, HII LIK UNG STANLEY, et al.Human health risk assessment of heavy metals in soil from a smelting plant based on bioaccessibility.[J].China Environmental Science, 2021,41(1):442-450.
[18]	Wang L, Lu X, Ren C, et al.Contamination assessment and health risk of heavy metals in dust from Changqing industrial park of Baoji, NW China[J].Environmental Earth Sciences, 2014,(71):2095-2104.
[19]	Yin P, Brauer M, Cohen A, et al.Long-term fine particulate matter exposure and nonaccidental and cause-specific mortality in a large national cohort of Chinese men[J].Environmental Health Perspectives, 2017,125(11):117002.
[20]	Pun V C, Kazemiparkouhi F, Manjourides J, et al.Long-term PM2.5 exposures and respiratory, cancer and cardiovascular mortality in American older adults[J].American Journal of Epidemiology, 2017, 186(8):961-969.
[21]	环境保护部.中国人群暴露参数手册(成人卷)[M].北京:中国环境出版社, 2013.Ministry of Environmental Protection.Exposure factors handbook of Chinese population, adults[M].Beijing:China Environmnetal Press, 2013.
[22]	Antoniadis V, Shaheen S M, Levizou E, et al.A critical prospective analysis of the potential toxicity of trace element regulation limits in soils worldwide:Are they protective concerning health risk assessment?-A review[J].Environment International, 2019,127:819-847.
[23]	林必桂,陈希超,杜宏伟,等.珠三角电子垃圾拆解区室内环境中多溴联苯醚的人体暴露[J].环境化学, 2018,37(9):1910-1920.Lin B G, Chen X C, Du H W, et al.Human exposure to PBDEs in indoor environment at an e-waste area in Pearl River Delta[J].Environmental Chemistry Environ.Chem., 2018,37(9):1910-1920.
[24]	环境保护部.中国人群暴露参数手册(儿童卷:6-17岁)[M].北京:中国环境出版社, 2016.Ministry of Environmental Protection.Exposure factors handbook of Chinese population, children (6-17years)[M].Beijing:China Environmnetal Press, 2016(in Chinese).
[25]	HJ 25.3-2019建设用地土壤污染风险评估技术导则[S].HJ 25.3-2019 Technical guidelines for risk assessment of soil contamination of land for construction[S].
[26]	陆喜红,吴丽娟,任兰,等.南京市PM2.5中重金属污染特征分析及健康风险评价[J].四川环境, 2016,35(6):115-119.Lu X H, Wu L J, Ren L, et al.Pollution characteristics analysis and health risk assessment of heavy metals in PM2.5 in Nanjing[J].Sichuan Environment, 2016,35(6):115-119.
[27]	姜杰,李瑞园,丘红梅,等.深圳大气PM2.5中重金属污染特征及健康风险评价[J].实用预防医学, 2019,26(7):781-785.Jiang J, Li R Y, Qiu H M, et al.Pollution characteristics and health risk assessment of heavy metals in ambient PM2.5 in Shenzhen[J].Practical Preventive Medicine, 2019,26(7):781-785.
[28]	EPA.Integrated risk information system[EB/Z] http://www.epa.gov/iris/, 1999.
[29]	EPA.Risk Assessment Guidance for Superfund (RAGS) Part A[EB/Z].https://www.epa.gov/sites/production/files/2015-09/documents/rags_a.pdf.2018-10-12.
[30]	ATSDR.Interaction profile for arsenic, cadimum, chromium, and lead[EB/Z].https://www.atsdr.cdc.gov/interactionprofiles/ip-metals1/ip04-p.pdf.2018-10-12.
[31]	GB 3095-2012环境空气质量标准[S].GB 3095-2012 Ambient air quality standards[S].
[32]	Johansson C, Norman M, Burman L.Road traffic emission factors for heavy metals[J].Atmospheric Environment, 2009,43(31):4681-4688.
[33]	李友平,刘慧芳,周洪,等.成都市PM2.5中有毒重金属污染特征及健康风险评价[J].中国环境科学, 2015,35(7):307-314.Li Y P, Liu H F, Zhou H, et al.Contamination characteristics and health risk assessment of toxic heavy metals in PM2.5 in Chengdu.[J].China Environmental Science, 2015,35(7):307-314.
[34]	Cao H, Zhu H, Jia Y, et al.Heavy metals in food crops and the associated potential for combined health risk due to interactions between metals[J].Human & Ecological Risk Assessment An International Journal, 2011,17(3):700-711.