Abstract:This study was designed to explore the effects of short-term exposure to PM10 on fasting plasma glucose and blood lipids in population with different glucose metabolism levels based on the platform of "Jinchang Cohort". The pollutant and meteorological data in Jinchang city from 2011 to 2017 were collected. Individual exposure levels were estimated by the nearest neighbor model. Generalized estimating equations were employed to analyze relationships between PM10, blood glucose and blood lipids. The exposure-response relationship curves were drawn by generalized additive mixed model. For every IQR increase in PM10 concentration, it was found that FPG, TC, LDL-C and HDL-C increased by 0.58mg/dL (95%CI:0.35, 0.82), 0.38mg/dL (95%CI:0.25, 0.52), 0.44mg/dL (95%CI:0.31, 0.57) and 0.34mg/dL (95%CI:0.29, 0.40), respectively, TG decreased by 0.67mg/dL (95%CI:-0.86,-0.47). With the increase of PM10 concentration, FPG, TC, LDL-C and HDL-C all showed an upward trend, while TG showed a downward trend. The adverse effects of PM10 on blood glucose and lipid indicators were greater in male and elder people. Findings suggest that PM10 was associated with changed fasting plasma glucose and blood lipid levels among population with different blood glucose states. Male and elder people should pay more attention to personal safety protection.
贺颖倩, 王敏珍, 郑山, 赵亚楠, 张露露, 刘婧, 白亚娜. PM10短期暴露对人群空腹血糖和血脂的影响[J]. 中国环境科学, 2022, 42(6): 2911-2920.
HE Ying-qian, WANG Min-zhen, ZHENG Shan, ZHAO Ya-nan, ZHANG Lu-lu, LIU Jing, BAI Ya-na. Effects of short-term exposure to PM10 on fasting plasma glucose and blood lipids. CHINA ENVIRONMENTAL SCIENCECE, 2022, 42(6): 2911-2920.
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