Oxidation and degradation mechanisms of ofloxacin by potassium ferrate
LI Ya-nan1, FENG Zhuo1, WANG Jia-qi1, GUO Kai1, ZHANG Guo-kai2
1. Department of Environmental Science and Engineering, Taiyuan University of Technology, Jinzhong 030600, China; 2. Chinasea Group Co. Ltd., Taiyuan 030012, China
Abstract：The oxidation and degradation mechanisms of quinolone antibiotic ofloxacin (OFL) by potassium ferrate (Fe (VI)) were studied. High performance liquid chromatography(HPLC), liquid chromatograph mass spectrometer(UPLC-QTOF-MS) and other methods were used to investigate the effects of Fe (VI) dosage, pH, temperature and coexisting substances on OFL removal, analyze the reaction kinetics, calculate the contribution rate of Fe(VI) in the process of OFL oxidation, identify the products of Fe(VI) and predict the main reaction pathways.The results show that the degradation efficiency of OFL reached 92.38% after 30 minutes of oxidation, with the molar ratio of Fe (VI) to OFL of 40:1, pH of 8 and temperature of 25 ℃. In the first 5 minutes' rapid reaction stage, OFL degradation conformed to pseudo second-order reaction kinetics, and the activation energy was 28.17kJ/mol. The contribution of Fe (VI) and the high-valent intermediate iron species to OFL removal was 70.34%, and humic acid significantly inhibited the reaction. Three main oxidation pathways for OFL degradation by Fe (VI) were proposed based on the analysis of reaction products, and the ring cleavages of quinolone, piperazine and oxazine rings were mainly achieved through decarboxylation, demethylation, decarbonylation and hydroxylation.
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