The CeO₂ doped Cu-Co-O/Al₂O₃ catalyst was prepared by ultrasonic-incipient wetness impregnation method using Al₂O₃ as a carrier. The catalytic activity of the prepared catalyst was investigated by catalytic combustion of VOCs. XRD, H²-TPR, SEM techniques were performed to characterize the catalyst. The results showed that the dispersion of active species increased after the doping of cerium oxide. Meanwhile, the reduction temperature of Cu-Co-O catalyst reduced. The activity evaluation results showed that inlet concentration could not greatly influence the catalytic performance of the prepared catalyst. The reaction temperature of toluene and xylene combustion decreased after the doping of Cerium, especially for toluene combustion.