西南典型菜地土壤重金属健康风险和毒性效应

摘要
图/表
参考文献
相关文章 (15)

全文: PDF (1204 KB) HTML (1 KB)
输出: BibTeX | EndNote (RIS)

摘要为揭示我国西南典型蔬菜种植区土壤中重金属的污染特征及人体健康风险，选择通海县菜地土壤为研究对象，分析了土壤中Cd、As、Pb、Cr、Ni、Cu和Zn的积累特征，结合体外胃肠模拟法（SBRC）和胃上皮细胞（GES-1）毒性实验评估土壤中重金属生物可给性与人体健康风险，并利用细胞毒性研究验证健康风险.结果表明：菜地土壤中7种重金属仅Cd的平均含量超出农用地土壤污染风险筛选值（GB 15618-2018），且变异系数（72.73%）最大；Cr、Cd和Zn的平均含量超出了云南省土壤背景值；土壤重金属生物可给性差异较大，Cd的生物可给性（35.31%）最高；研究区可能存在由重金属引起的致癌风险，非致癌风险不明显，Cr、As和Ni是致癌风险的主要贡献元素；基于生物可给性的综合非致癌风险（HI）和综合致癌风险（CR）均小于基于总量的评价结果；健康风险的细胞毒性验证实验表明生物可给态重金属暴露后抑制了细胞活性，改变细胞形态，诱发了明显的胃上皮细胞损伤.

	服务

	把本文推荐给朋友
	加入我的书架
	加入引用管理器
	E-mail Alert
	RSS
	作者相关文章
	田稳
	宗大鹏
	方成刚
	王成尘
	王健敏
	向萍

关键词 ：土壤, 重金属, 健康风险, 细胞毒性

Abstract：To figure out the pollution characteristics of heavy metals in soils from typical vegetable planting areas in Tonghai, southwest China, we collected 151soil samples and measured the concentrations of Cd, As, Pb, Cr, Ni, Cu, and Zn. Besides, the bioaccessibility and cytotoxicity of heavy metals were investigated by in vitro gastrointestinal simulation method (SBRC) combined with the human gastric mucosa cells GES-1model. Our results showed that the Cd level in soils exceeded the risk screening value (0.6mg/kg, 6.5 < pH £ 7.5, GB 15618-2018) with the greatest coefficient of variation being 72.73%. The average content of Cr, Cd, and Zn exceeded the soil background values of Yunnan Province. In addition, the bioaccessibility of heavy metals in soil varied greatly, with Cd being the highest at 35.31%. There may be carcinogenic risk caused by metals in the study area, where Cr, As and Ni were the main contributors to carcinogenic risks. However, the non-carcinogenic risk was not obvious. The comprehensive non-carcinogenic risk (HI) and comprehensive carcinogenic risk (CR) based on bioaccessibility data were both lower than those based on total concentrations. To validate the above-mentioned results, GES-1cells were employed and exposed to all bioaccessible extracts of soils, cell viability significantly decreased (P<0.05), and cell morphology was altered in all groups, indicating bioaccessible extracts of soils could induce gastric epithelial cell damage.

Key words： soil heavy metals health risk cytotoxicity

收稿日期: 2022-03-07

PACS:

X53

基金资助:国家自然科学基金资助项目（41967026，21906134）；云南省创新团队项目（202005AE160017）；云南省农业基础研究联合专项重点项目（202101BD070001-023）；云南基础研究计划面上项目（2019FB014）；国家林业和草原局林草科技创新青年拔尖人才项目（2020132613）；云南省高层次人才引进计划青年人才项目（YNQR-QNRC-2018-049）

通讯作者: 向萍,研究员,xiangping@swfu.edu.cn E-mail: xiangping@swfu.edu.cn

作者简介: 田稳(1996-),男,贵州盘州人,西南林业大学硕士研究生,主要从事土壤污染与农产品安全等方面的研究.发表论文8篇.

引用本文:

田稳, 宗大鹏, 方成刚, 王成尘, 王健敏, 向萍. 西南典型菜地土壤重金属健康风险和毒性效应[J]. 中国环境科学, 2022, 42(10): 4901-4908. TINA Wen, ZONG Da-peng, FANG Cheng-gang, WANG Cheng-chen, WANG Jian-min, XIANG Ping. Health risk and toxic effect of heavy metals in soils from typical vegetable planting areas in southwest China. CHINA ENVIRONMENTAL SCIENCECE, 2022, 42(10): 4901-4908.

链接本文:

http://www.zghjkx.com.cn/CN/ 或 http://www.zghjkx.com.cn/CN/Y2022/V42/I10/4901

[1]	中华人民共和国生态环境部.2014中国生态环境状况公报[R].北京, 2015.Ministry of Environmental Protection of the People's Republic of China.Bulletin of China's environment in 2014[R].Beijing, 2015.
[2]	Meng M, Yang L S, Wei B G, et al.Plastic shed production systems:The migration of heavy metals from soil to vegetables and human health risk assessment[J].Ecotoxicology and Environmental Safety, 2021,215:112106.
[3]	Lu Y L, Song S, Wang R S, et al.Impacts of soil and water pollution on food safety and health risks in China[J].Environment International, 2015,77:5-15.
[4]	叶脉,张景茹,张路路,等.广东鼻咽癌高发区土壤-作物系统重金属迁移特征及健康风险评价[J].环境科学, 2020,41(12):5579-5588.Ye M, Zhang J R, Zhang L L, et al.Transfer factor and health risk assessment of heavy metals in a soil-crop system in a high incidence area of nasopharyngeal carcinoma, Guangdong[J].Environmental Science, 2020,41(12):5579-5588.
[5]	US EPA.Risk assessment guidance for superfund:volume Ⅲ-Part A, process for conducting probabilistic risk assessment[R].Washington, 2001.
[6]	Zeng S Y, Ma J, Yang Y J, et al.Spatial assessment of farmland soil pollution and its potential human health risks in China[J].Science of the Total Environment, 2019,687:642-653.
[7]	刘南婷,刘鸿雁,吴攀,等.典型喀斯特地区土壤重金属累积特征及环境风险评价[J].农业资源与环境学报, 2021,38(5):797-809.Liu N T, Liu H Y, Wu P, et al.Accumulation characteristics and environmental risk assessment of heavy metals in typical karst soils[J].Journal of Agricultural Resources and Environment, 2021,38(5):797-809.
[8]	Li Y, Padoan E, Ajmone-marsan F.Soil particle size fraction and potentially toxic elements bioaccessibility:A review[J].Ecotoxicology and Environmental Safety, 2021,209:111806.
[9]	林承奇,蔡宇豪,胡恭任,等.闽西南土壤-水稻系统重金属生物可给性及健康风险[J].环境科学, 2021,42(1):359-367.Lin C Q, Cai Y H, Hu G R, et al.Bioaccessibility and health risks of the heavy metals in soil-rice system of southwest Fujian Province[J].Environmental Science, 2021,42(1):359-367.
[10]	李梦莹,王成尘,毕珏,等.食品中重金属的人体健康风险评估方法研究进展[J].福建农林大学学报(自然科学版), 2021,50(1):1-9.Li M Y, Wang C C, Bi J, et al.Human health risk assessment of heavy metals in food:a review[J].Journal of Fujian Agriculture and Forestry University (Natural Science Edition), 2021,50(1):1-9.
[11]	Li H B, Li M Y, Zhao D, et al.Arsenic, lead, and cadmium bioaccessibility in contaminated soils:Measurements and validations[J].Critical Reviews in Environmental Science and Technology, 2019,50(13):1303-1338.
[12]	Ma J Y, Bao X C, Tian W, et al.Effects of soil-extractable metals Cd and Ni from an e-waste dismantling site on human colonic epithelial cells Caco-2:Mechanisms and implications[J].Chemosphere, 2021, 292:133361.
[13]	张蒙蒙,张超艳,郭晓欣,等.焦化场地包气带区土壤苯的精细化风险评估[J].环境科学研究, 2021,34(5):1223-1230.Zhang M M, Zhang C Y, Guo X X, et al.Refined risk assessment of soil benzene in unsaturated zone of coking site[J].Research of Environmental Sciences, 2021,34(5):1223-1230.
[14]	Zhong M S, Jiang L.Refining health risk assessment by incorporating site-specific background concentration and bioaccessibility data of Nickel in soil[J].Science of the Total Environment, 2017,581-582:866-873.
[15]	Li S Z, Zhao B, Jin M, et al.A comprehensive survey on the horizontal and vertical distribution of heavy metals and microorganisms in soils of a Pb/Zn smelter[J].Journal of Hazardous Materials, 2020,400:123255.
[16]	Varol M, Gunduz K, Sunbul M R.Pollution status, potential sources and health risk assessment of arsenic and trace metals in agricultural soils:A case study in Malatya province, Turkey[J].Environmental Research, 2021,202:111806.
[17]	Wang F F, Guan Q Y, Tian J, et al.Contamination characteristics, source apportionment, and health risk assessment of heavy metals in agricultural soil in the Hexi Corridor[J].Catena, 2020,191:104573.
[18]	Zhang R, Chen T, Zhang Y, et al.Health risk assessment of heavy metals in agricultural soils and identification of main influencing factors in a typical industrial park in northwest China[J].Chemosphere, 2020,252:126591.
[19]	GB15618-2018土壤环境质量农用地土壤污染风险管控标准[S].GB15618-2018 Soil environmental quality risk control standard for soil contamination of agricultural soil[S].
[20]	马娇阳,田稳,王坤,等.污染场地土壤重金属的生物可给性及毒性研究[J].中国环境科学, 2021,41(10):4885-4893.Ma J Y, Tian W, Wang K, et al.Bioaccessibility and their toxic effects of heavy metal in field soils from an electronic disassembly plant[J].China Environmental Science, 2021,41(10):4885-4893.
[21]	Li M Y, Qin Y S, Wang C C, et al.Total and bioaccessible heavy metals in cabbage from major producing cities in Southwest China:health risk assessment and cytotoxicity[J].RSC Advances, 2021, 11(20):12306-12314.
[22]	沐婵,黄翠菊,钱荣青,等.2004~2015年通海县露地蔬菜基地土壤养分变化[J].农学学报, 2021,11(1):22-26.Mu C, Huang C J, Qian R Q, et al.Soil nutrient changes in field vegetable base in tonghai from 2004 to 2015[J].Journal of Agriculture, 2021,11(1):22-26.
[23]	中国环境监测总站.中国土壤元素背景值[M].北京:中国环境科学出版社, 1990:330-381.China National Environmental Monitoring Centre.The soil environmental background value in the People's Public of China[M].Beijing:China Environmental Science Press, 1990:330-381.
[24]	汪洁,龚竞,刘雨佳,等.昆明市土壤重金属污染特征及其生态与健康风险评价[J].轻工学报, 2022,37(4):118-126.Wang J, Gong J, Liu Y J, et al.Ecological & health risk assessment of heavy metals in soils from a typical southwest capital city[J].Journal of Light Industry, 2022,37(4):118-126.
[25]	Bai J H, Xiao R, Gong A, et al.Assessment of heavy metal contamination of surface soils from typical paddy terrace wetlands on the Yunnan Plateau of China[J].Physics and Chemistry of the Earth, Parts A/B/C, 2011,36(9-11):447-450.
[26]	董达诚,胡梦淩,罗昱,等.陆良县菜地土壤重金属的污染评价及来源解析[J].环境污染与防治, 2021,43(6):732-737,790.Dong D C, Hu M L, Luo Y, et al.Pollution evaluation and source apportionment of heavy metals in vegetable fields of Luliang County[J].Environmental Pollution & Control, 2021,43(6):732-737,790.
[27]	Lian Z M, Zhao X M, Gu X, et al.Presence, sources, and risk assessment of heavy metals in the upland soils of northern China using Monte Carlo simulation[J].Ecotoxicology and Environmental Safety, 2022,230:113154.
[28]	冯英,马璐瑶,王琼,等.我国土壤-蔬菜作物系统重金属污染及其安全生产综合农艺调控技术[J].农业环境科学学报, 2018, 37(11):2359-2370.Feng Y, Ma L Y, Wang Q, et al.Heavy-metal pollution and safety production technologies of soil-vegetable crop systems in China[J].Journal of Agro Environment Science, 2018,37(11):2359-2370.
[29]	李相楹,何腾兵,付天岭,等.重金属元素在土壤-蔬菜系统中的迁移富集及其毒性机理研究进展[J].应用化工, 2021,50(7):1932-1937.Li X Y, He T B, Fu T L, et al.Review of migration, bioaccumulation and toxicity of heavy metals in soil-vegetables system[J].Applied Chemical Industry, 2021,50(7):1932-1937.
[30]	Guo J K, Zhang Y, Liu W J, et al.Incorporating in vitro bioaccessibility into human health risk assessment of heavy metals and metalloid (As) in soil and pak choi (Brassica chinensis L.) from greenhouse vegetable production fields in a megacity in Northwest China[J].Food Chemistry, 2022,373:131488.
[31]	Hou D, O'connor D, Igalavithana A D, et al.Metal contamination and bioremediation of agricultural soils for food safety and sustainability[J].Nature Reviews Earth & Environment, 2020,1(7):366-381.
[32]	Liu J, Wang Y N, Liu X M, et al.Occurrence and health risks of heavy metals in plastic-shed soils and vegetables across China[J].Agriculture, Ecosystems & Environment, 2021,321:107632.
[33]	Zhang Y Q, Wang S T, Gao Z J, et al.Contamination characteristics, source analysis and health risk assessment of heavy metals in the soil in Shi River Basin in China based on high density sampling[J].Ecotoxicology and Environmental Safety, 2021,227:112926.
[34]	Zhang J, Baralkiewicz D, Wang Y, et al.Arsenic and arsenic speciation in mushrooms from China:A review[J].Chemosphere, 2020,246:125685.
[35]	Kumar A, Jigyasu D K, Kumar A, et al.Nickel in terrestrial biota:Comprehensive review on contamination, toxicity, tolerance and its remediation approaches[J].Chemosphere, 2021,275:129996.
[36]	马娇阳,保欣晨,王坤,等.土壤镉污染的人体健康风险评价研究:生物有效性与毒性效应[J].生态毒理学报, 2021,16(6):120-132.Ma J Y, Bao X C, Wang K, et al.Human health risk assessment of cadmium in soils:role of bioavailability and toxic effects[J].Asian Journal of Ecotoxicology, 2021,16(6):120-132.
[37]	Xiang P, Liu R Y, Li C, et al.Effects of organophosphorus flame retardant TDCPP on normal human corneal epithelial cells:Implications for human health[J].Environmental Pollution, 2017,230:22-30.
[38]	Wang K, Ma J Y, Li M Y, et al.Mechanisms of Cd and Cu induced toxicity in human gastric epithelial cells:Oxidative stress, cell cycle arrest and apoptosis[J].Science of the Total Environment, 2021,756:143951.